| UDP-N-acetylglucosamine-lysosomal-enzyme-N-acetylglucosaminephosphotransferase | <enzyme> Fibroblasts from patients with i-cell (mucolipidosis II) and pseudo-hurler polydystrophy (mucolipidosis III) are deficient in above enzyme; for n-acetylglucosamine transferred to dolichyl phosphate see EC 2.7.8.15 Registry number: EC 2.7.8.17 Synonym: udpgnac gp gnac phosphotransferase, udpgnac phosphotransferase, uridine 5'-diphosphate-n-acetylglucosamine glycoprotein n-acetylglucosaminylphosphotransferase, n-acetylglucosamine-1-phosphotransferase, n-agapt, udp-n-acetylglucosamine-lysosomal glycoprotein n-acetylglucosaminylphosphotransferase, udp-acetylglucosamine-glycoprotein n-acetylglucosamine-1-phosphotransferase (26 Jun 1999) |
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| UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosaminyl-1-phosphotransferase | <enzyme> An enzyme that participates in the posttranslational modification of a number of lysosomal proteins; a deficiency or defect in this enzyme results in two forms of mucolipidoses, I-cell disease, and pseudo-Hurler polydystrophy. (05 Mar 2000) |
| Kornberg enzyme | DNA polymerase I from Escherichia coli. (05 Mar 2000) |
| 1,4-alpha-glucan branching enzyme | <enzyme> In glycogen or amylopectin synthesis, the enzyme that catalyses the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a similar glucan chain. Chemical name: 1,4-alpha-D-Glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase Registry number: EC 2.4.1.18 (12 Dec 1998) |
| liver enzyme | <biochemistry> Special proteins found in the cells of the liver that are responsible for catalysing specific metabolic reactions. They may become elevated in the bloodstream in conditions of hepatitis or liver cancer. See: liver function tests. (27 Sep 1997) |
| lysosomal enzyme | <biochemistry> A range of degradative enzymes, most of which operate best at acid pH. The best known marker enzymes are acid phosphatase and glucuronidase, but many others are known. (18 Nov 1997) |
| absolute system of units | A system based on absolute units accepted as being fundamental (length, mass, time) and from which other units (force, energy or work, power) are derived; such system's in common use are the foot-pound-second, centimeter-gram-second, and meter-kilogram-second system's. (05 Mar 2000) |
| absorbent system | <anatomy> The tissues and organs (including the bone marrow, spleen, thymus and lymph nodes) that produce and store cells that fight infection and the network of vessels that carry lymph. (12 May 1997) |
| alimentary system | The organs that are responsible for getting food into and out of the body and for making use of food to keep the body healthy. These include the mouth, oesophagus, stomach, liver, gallbladder, pancreas, small intestine, colon, and rectum. (12 Dec 1998) |
| anterolateral system | A composite bundle of fibres, located in the ventrolateral part of the lateral funiculus, containing spinothalamic, spinohypothalamic, spinoreticular, and spinomesencephalic (spinotectal, spinal to periaqueductal grey, etc.) fibres; occupies the combined areas of the spinal white matter historically divided into anterior and lateral spinothalamic tracts; located in white matter ventral to the denticulate ligament, hence the anatomical basis for the anterolateral cordotomy; concerned with the transmission of nociceptive and thermal information and with crude (nondiscriminative) touch. (05 Mar 2000) |
| anti-allergic and respiratory system agents | A collective term for drugs used to treat allergic reactions as well as those drugs that produce an effect on the respiratory system. (12 Dec 1998) |
| arch-loop-whorl system | See: Galton's system of classification of fingerprints. (05 Mar 2000) |
| association system | Groups or tracts of nerve fibres interconnecting different regions of one and the same major subdivision of the central nervous system, such as the various areas of the cerebral cortex or the various segments of the spinal cord. (05 Mar 2000) |
| autonomic nervous system | <anatomy> Neurons that are not under conscious control, comprising two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g., of the gut), and glands. The autonomic nervous system has two divisions: 1. The sympathetic nervous system that accelerates the heart rate, constricts blood vessels, and raises blood pressure. 2. The parasympathetic nervous system slows the heart rate, increases intestinal and gland activity, and relaxes sphincter muscles. (03 Jul 1999) |
| autonomic nervous system diseases | Diseases that have their major effects on the autonomic nervous system. The autonomic nervous system may be seriously affected in many other disorders including other peripheral nervous system diseases, infectious diseases (e.g., tetanus, diphtheria), immunologic diseases (e.g., acquired immunodeficiency syndrome), and systemic disorders (e.g., diabetic neuropathy, amyloid neuropathy, thyroid diseases). Disorders of central autonomic control also contribute substantially to a wide variety of problems (e.g., eating disorders, panic disorder, water-electrolyte imbalance, cardiovascular diseases). (12 Dec 1998) |