| carbonyl cyanide p-trifluoromethoxyphenylhydrazone | <chemical> A proton ionophore that is commonly used as an uncoupling agent in biochemical studies. Pharmacological action: ionophores, uncoupling agents. Chemical name: Propanedinitrile, ((4-(trifluoromethoxy)phenyl)hydrazono)- (12 Dec 1998) |
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| carbonyl group | A group in which an oxygen atom is double-bonded to a carbon atom: O=C. The carbon atom then has two additional bonds to attach to the rest of the molecule. Organic molecules containing a carbonyl group are a very important, major group of compounds studied in the field of organic chemistry. (09 Oct 1997) |
| carboplatin | An injected chemotherapydrug which is typically used to treat advancedovarian cancer (carcinoma).Side effects include lowered blood cellcounts (all types), nausea and diarrhoea, hair loss, pain and otherneurologic problems. (09 Oct 1997) |
| carboprost | <chemical> An abortifacient effective in both the first and second trimesters of pregnancy. Pharmacological action: abortifacient agents, non-steroidal, oxytocics. Chemical name: Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9alpha,11alpha,13E,15S)- (12 Dec 1998) |
| carboprost tromethamine | C25H38O5;a prostaglandin used as an abortifacient and in the treatment of refractory postpartum bleeding. (05 Mar 2000) |
| carboxamide | A molecular configuration (-CONH2) that, together with the related carboximides (iminocarbonyls) (-CONH-), is a constituent of many hypnotics, including barbiturates, hydantoins, and thiazines. Synonym: aminocarbonyl. (05 Mar 2000) |
| carboxamidopeptidase | <enzyme> Has both trypsin and chymotrypsin-like activities; neurohypophyseal hormone inactivating peptidase from toad skin Registry number: EC 3.4.21.- (26 Jun 1999) |
| carboximide | See: carboxamide. (05 Mar 2000) |
| carboxin | <chemical> A systemic agricultural fungicide and seed treatment agent. Pharmacological action: fungicides, industrial. Chemical name: 1,4-Oxathiin-3-carboxamide, 5,6-dihydro-2-methyl-N-phenyl- (12 Dec 1998) |
| carboxy terminal | The end of a peptide or protein having a free carboxyl (-COOH) group. (05 Mar 2000) |
| carboxy- | Combining form indicating addition of CO or CO2. (05 Mar 2000) |
| carboxy-lyases | <enzyme> Enzymes that catalyze the nonhydrolytic addition or removal of a carboxyl group to or from a compound. They include the carboxylases and decarboxylases. Registry number: EC 4.1.1. (12 Dec 1998) |
| carboxy-terminal domain kinase | <enzyme> Protein kinase that phosphorylates the c-terminal repeat domain of the largest subunit of RNA polymerase II at serine residues Registry number: EC 2.7.1.- Synonym: ctd kinase, hs-ctd kinase, tfiih-associated ctd kinase (26 Jun 1999) |
| carboxycathepsin | <enzyme> A hydrolase cleaving C-terminal dipeptides from a variety of substrates, including angiotensin I, which is converted to angiotensin II and histidylleucine. An important step in the metabolism of certain vasopressor agents. It is a chloride-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. Only single dipeptides are released from angiotensin I and bradykinin because of the lack of activity on bonds involving proline. It may also have endopeptidase activity on some substrates. Registry number: EC 3.4.15.1 Synonym: carboxycathepsin, dipeptidyl carboxypeptidase, kinase II, peptidase P. (22 Sep 2002) |
| carboxydismutase | A dimerizing carboxy-lyase; an enzyme that catalyses the addition of carbon dioxide to d-ribulose 1,5-bisphosphate and the hydrolysis of the addition product to two molecules of 3-d-phosphoglyceric acid, a key reaction in the fixation of CO2 in photosynthesis. Synonym: carboxydismutase. (05 Mar 2000) |