| transforming factor | The DNA responsible for bacterial transformation. (05 Mar 2000) |
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| transforming gene | <molecular biology> Genes, originally of tumour viruses, responsible for their ability to transform cells. The term now serves as an operational definition of oncogenes. (18 Nov 1997) |
| transforming growth factor | <growth factor> Proteins secreted by transformed cells that can stimulate growth of normal cells. Unfortunate misnomer, since they induce aspects of transformed phenotype, such as growth in semi solid agar, but do not actually transform. Transforming growth factor alpha, 50 amino acid polypeptide originally isolated from viral transformed rodent cells, contains EGF like domain and binds to EGF receptor. Stimulates growth of microvascular endothelial cells, i.e. Is angiogenic. Transforming growth factor beta a homodimer of two 112 chains, polypeptide is secreted by many different cell types, stimulates wound healing but in vitro is also a growth inhibitor for certain cell types. The transforming growth factor family includes many of the bone morphogenetic proteins. Acronym: TGF (18 Nov 1997) |
| transforming growth factor alpha | Factor isolated in a variety of tissues including epithelium, and maternal decidua. It is closely related to epidermal growth factor (epidermal growth factor-urogasterone) and binds to the egf receptor. Tgf-alpha acts synergistically with tgf-beta in inducing phenotypic transformation, but its physiological role is unknown. (12 Dec 1998) |
| transforming growth factor beta | Factor synthesised in a wide variety of tissues including platelets, placenta, and both normal and transformed cell lines. It acts synergistically with tgf-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. Tgf-beta also has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. There are at least three forms of tgf-beta: tgf-beta1, tgf-beta2, and tgf-beta1.2. The latter is a heterodimer made up of both tgf-beta1 and tgf-beta2. (12 Dec 1998) |
| transforming growth factors | <chemical> Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumour-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, transforming growth factor alpha and transforming growth factor beta. Chemical name: Animal growth regulators, transforming growth factors (12 Dec 1998) |
| transforming oncogene | <molecular biology> A gene that upon transfection converts a previously immortalised cell to the malignant phenotype. (09 Oct 1997) |
| transforming virus | <molecular biology, virology> Viruses capable of inducing malignant transformation of animal cells in culture. Among the Oncovirinae, nondefective viruses that lack oncogenes can induce tumours such as leukaemias in animals, but cannot transform in vitro. On acquisition of oncogenes they become (acute) transforming viruses. (18 Nov 1997) |
| transformism | <biology> The hypothesis, or doctrine, that living beings have originated by the modification of some other previously existing forms of living matter; opposed to abiogenesis. Origin: F. Transformisme. Source: Websters Dictionary (01 Mar 1998) |
| transfuse | 1. To pour, as liquid, out of one vessel into another; to transfer by pouring. 2. <medicine> To transfer, as blood, from the veins or arteries of one man or animal to those of another. 3. To cause to pass from to another; to cause to be instilled or imbibed; as, to transfuse a spirit of patriotism into a man; to transfuse a love of letters. "Into thee such virtue and grace Immense I have transfused." (Milton) Origin: L. Transfusus, p. P. Of transfundere: cf. F. Transfuser. See Transfund. Source: Websters Dictionary (01 Mar 1998) |
| transfusion | <haematology> The introduction of whole blood or blood component directly into the blood stream. Compare: infusion. Origin: L. Transfusio (18 Nov 1997) |
| transfusion hepatitis | A virus disease with a long incubation period (usually 50 to 160 days), caused by hepatitis B virus, a DNA virus and member of the family Hepadnoviridae, usually transmitted by injection of infected blood or blood derivatives or by use of contaminated needles, lancets, or other instruments; clinically and pathologically similar to viral hepatitis type A, but there is no cross-protective immunity; HBsAg is found in the serum and the hepatitis delta virus occurs in some patients. Synonym: hepatitis B, serum hepatitis, transfusion hepatitis, virus B hepatitis. (05 Mar 2000) |
| transfusion nephritis | Renal failure and tubular damage resulting from the transfusion of incompatible blood; the haemoglobin of the haemolyzed red cells is deposited as casts in the renal tubules. (05 Mar 2000) |
| transfusion reaction | A reaction to a blood transfusion secondary to some incompatibility in type, RH factor or other surface antigens. May be manifest by haemolytic anaemia, heart failure, and-or renal failure. Symptoms include facial flushing, angioedema, headache, wheezing, anaphylaxis, shock, fever, chills and breathing difficulty. (27 Sep 1997) |
| transgelin | <protein> Transformation and shape change sensitive isoform of 21 kD actin binding protein. Highly conserved (as far back as yeast), binds F actin (1:6 transgelin:G actin) and causes gelation. Similar, but not identical, to calponin. (18 Nov 1997) |
Synonyms : Transfer, Learning Transfer, Training Transfer, Transfers (Psychology)
Synonyms : Agreement, Transfer, Agreements, Transfer, Transfer Agreements
Synonyms : Dialyzable Leukocyte Extract, Extract, Dialyzable Leukocyte, Factor, Transfer, Leukocyte Extract, Dialyzable
Synonyms : Amino Acid Activation, Translational, Transfer RNA Acylation, Transfer RNA Amino Acylation, tRNA Acylation, tRNA Amino Acylation, Acylation, Transfer RNA, Acylation, tRNA, Acylations, Transfer RNA, Acylations, tRNA, Amino Acylation, tRNA, Aminoacylation, tRNA
Synonyms : Transferase
| transurethral resection of the prostate |
removal of significant amounts of prostate tissue (as in cases of benign prostatic hyperplasia)
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| transverse |
cross(a): extending or lying across; in a crosswise direction; at right angles to the long axis; "cross members should be all steel"; "from the transverse hall the stairway ascends gracefully"; "transversal vibrations"; "transverse colon"
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| transvestitism |
transvestism: the practice of adopting the clothes or the manner or the sexual role of the opposite sex
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| transformer |
an electrical device by which alternating current of one voltage is changed to another voltage
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| transfuse |
instill: impart gradually; "Her presence instilled faith into the children"; "transfuse love of music into the students" pour out of one vessel into another cup: treat by applying evacuated cups to the patient's skin give a transfusion (e.g., of blood) to
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| trans | elevate or idealize, in allusion to Christ's transfiguration |
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| trans | pierce with a sharp stake or point |
| trans | to render motionless, as with a fixed stare or by arousing terror or awe |
| trans | having your attention fixated as though by a spell |
| trans | change in outward structure or looks |
| trans | physics: increase or decrease (an alternating current or voltage) |
| trans | biology: change (a bacterial cell) into a genetically distinct cell by the introduction of DNA from another cell of the same or closely related species |
| trans | physics: convert (one form of energy) to another |
| trans | change or alter in form, appearance, or nature |
| trans | change from one form or medium into another |
| trans | subject to a mathematical transformation |
| trans | capable of being changed in substance as if by alchemy |