| IgA-specific serine endopeptidase | <enzyme> Extracellular microbial enzymes whose only substrate is human IgA of the iga1 subclass; cleave the immunoglobulin at a specific internal prolyl-threonyl peptide bond in the heavy chain to yield intact faba and fca fragments; consider also EC 3.4.24.13 Registry number: EC 3.4.21.72 Synonym: immunoglobulin a(1) protease, iga1 protease, immunoglobulin a1 protease, IgA protease (26 Jun 1999) |
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| organ-specific | Denoting or pertaining to a serum produced by the injection of the cells of a certain organ or tissue that, when injected into another animal, destroys the cells of the corresponding organ. (05 Mar 2000) |
| organ-specific antigen | A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species. Synonym: tissue-specific antigen. (05 Mar 2000) |
| tail-specific protease | <enzyme> Selectively degrades proteins with nonpolar c termini Registry number: EC 3.4.99.- Synonym: tsp protease, prc protein, prc gene product (26 Jun 1999) |
| tissue-specific antigen | A heterogenetic antigen with organ specificity; e.g., in addition to species-specific antigen, kidney of one species contains antigen that is identical to that in kidney of other species. Synonym: tissue-specific antigen. (05 Mar 2000) |
| tumour specific antigen | <immunology, oncology> Antigen on tumour cells detected by cell-mediated immunity. For virus transformed cells TSTA (unlike T antigen) is found to differ for different individual tumours induced by the same virus. May consist of fragments of T antigens exposed at the cell surface. (18 Nov 1997) |
| tumour-specific transplantation antigens | Surface antigen's of DNA tumour virus-transformed cells, which elicit an immune rejection of the virus-free cells when transplanted into an animal that has been immunised against the specific cell-transforming virus. (05 Mar 2000) |
| uridine-specific acid nuclease | <enzyme> Chicken liver enzyme hydrolyzes poly(u) and e. Coli RNA Registry number: EC 3.1.- (26 Jun 1999) |
| fluoroacetate-specific dehalogenase | <enzyme> Acts on fluoroacetamide at 0.1 the rate for fluoroacetate Registry number: EC 3.8.1.- Synonym: fluoroacetate-specific defluorinase, fac dehalogenase (26 Jun 1999) |
| law of specific nerve energies | Each type of sensory nerve ending, however stimulated (electrically, mechanically, etc.), gives rise to its own specific sensation; moreover, each type of sensation depends not upon any special character of the different nerves but upon the part of the brain in which their fibres terminate. Synonym: law of specific nerve energies. (05 Mar 2000) |
| lymphocyte specific protein tyrosine kinase p56(lck) | <enzyme> This enzyme is a lymphoid specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the il-2 receptor, and is thought to be involved in the earliest steps of tcr-mediated T-cell activation. Registry number: EC 2.7.11.- (12 Dec 1998) |