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protein-bound i. iodine bound to protein in the blood serum, measured in the protein-bound iodine test.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
protein-bound iodine t. a formerly common thyroid function test in which the amount of iodine firmly bound to protein in the serum was determined by precipitating the proteins, yielding an estimate of serum thyroid hormone concentration. Errors were introduced if iodine compounds from nonthyroid sources were present.
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protein-energy m. a class of disorders caused by varying degrees of protein and calorie deficiency, alone or in combination, frequently aggravated by accompanying physiologic and environmental stresses. It may be primary, including such disorders as marasmus, kwashiorkor, and marasmic kwashiorkor, or secondary to other diseases.
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protein-glutamine γ-glutamyltransferase [EC 2.3.2.13] an enzyme of the transferase class that creates crosslinks within and between fibrin molecules, transferring the glutamyl portion of glutamine side chains to the amino group of lysine side chains: protein-glutamine + lysine-protein = protein-glutamyl lysine-protein + NH3. The resultant polymerization of fibrin is an important part of blood clotting. It is the activated form of coagulation factor XIII (coagulation factor XIIIa). Called also transglutaminase.
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protein-losing e. a nonspecific term referring to conditions associated with excessive enteric loss of plasma protein. It occurs in extensive ulceration (e.g., inflammatory bowel disease), diffuse mucosal disease (e.g., adult celiac disease) in which there is more rapid desquamation of mucosal epithelial cells, and in intestinal lymphatic obstruction (intestinal lymphangiectasia).
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