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phosphohexokinase <enzyme> An enzyme that catalyses the conversion of a nucleotide triphosphate and a sugar phosphate to a nucleotide diphosphate and a sugar diphosphate. D-fructose 6-phosphate, d-tagatose 6-phosphate, and sedoheptulose 7-phosphate can act as acceptors; ATP, utp, ctp, and itp can act as donors. A deficiency of this enzyme is the cause of glycogen storage disease type vii.
Chemical name: ATP:D-fructose-6-phosphate 6-phosphotransferase
Registry number: EC 2.7.1.11
(12 Dec 1998)
phosphohexomutase <enzyme> An enzyme that catalyses the reversible interconversion of d-fructose 6-phosphate and d-glucose-6-phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver glycogenesis and haemolytic anaemia.
Synonym: hexosephosphate isomerase, phosphohexomutase, phosphohexose isomerase.
(05 Mar 2000)
phosphohexose isomerase <enzyme> An enzyme that catalyses the reversible interconversion of d-fructose 6-phosphate and d-glucose-6-phosphate; a part of glycolysis and gluconeogenesis; glucosephosphate isomerase deficiency is an inherited disorder resulting in liver glycogenesis and haemolytic anaemia.
Synonym: hexosephosphate isomerase, phosphohexomutase, phosphohexose isomerase.
(05 Mar 2000)
phosphohexose isomerase deficiency <enzyme> An enzyme deficiency characterised by chronic nonspherocytic haemolytic anaemia; autosomal recessive inheritance.
Synonym: phosphohexose isomerase deficiency.
(05 Mar 2000)
phosphohydrolases Phosphoric monoester hydrolases;enzymes (EC sub-subclass 3.1.3) cleaving phosphoric acid (as orthophosphate) from its esters; trivial names usually end in phosphate.
(05 Mar 2000)
phosphoinositide <biochemistry> A phosphatidic acid combined with inositol found in biomembranes and a precursor to certain cellular signals. Sometimes referred to as inositide.
It is a very important minor phospholipid in eukaryotes, involved in signal transduction processes. Contains myo inositol linked through the 1 hydroxyl group to phosphatidic acid.
The 4 phosphate (PIP) and 4, 5 bisphosphate derivatives PIP2) are formed and broken down in membranes by the action of specific kinases and phosphatases (futile cycles).
Signal sensitive phospholipase C enzymes remove the inositol moiety, in particular from 1,4,5 trisphosphate (PIP2) as inositol 1,4,5 triphosphate (Ins P3: IP3). Both the diacyl glycerol and products act as second messengers.
Synonym: phosphoinositide.
(20 Sep 2002)
phosphokinase A phosphotransferase or a kinase.
(05 Mar 2000)
phospholamban kinase <enzyme> A delta-cam kinase isozyme; catalyses the phosphorylation of phospholamban
Registry number: EC 2.7.1.-
Synonym: phospholamban sarcoplasmic reticulum calmodulin-dependent protein kinase, phospholamban srcam kinase
(26 Jun 1999)
phospholamban phosphatase <enzyme> Purified from canine cardiac cytosol; dephosphorylates pholamban; stimulated by mg+2, mn+2 or ca+2
Registry number: EC 3.1.3.-
(26 Jun 1999)
phospholipase <enzyme> That hydrolyse ester bonds in phospholipids. They comprise two types: aliphatic esterases (phospholipase A1, A2 and B) that release fatty acids and phosphodiesterases (types C and D) that release diacyl glycerol or phosphatidic acid respectively.
Type A2 is widely distributed in venoms and digestive secretions. Types A1, A2 and C the latter specific for phosphatidyl inositol) are present in all mammalian tissues. Type C is also found as a highly toxic secretion product of pathogenic bacteria. Type B attacks monoacyl phospholipids and is poorly characterised. Type D is largely of plant origin. PLA2 Type II (a secreted enzyme, but not the same as the Type I digestive pancreatic enzyme) is probably very important in inflammation because its action can release arachidonic acid, the starting point for eicosanoid synthesis.
Phosphatidyl inositol bisphosphate specific phospholipase C is important in generating diacyl glycerol and inositol trisphosphate, both second messengers.
(31 Dec 1997)
phospholipase A1 <enzyme> An enzyme that hydrolyzes a lecithin (1,2-diacylglycerophosphocholine) to a 2-acylglycerophosphocholine and a fatty acid anion.
(05 Mar 2000)
phospholipase A2 <enzyme> An enzyme that catalyses the hydrolysis of a lecithin to a lysolecithin by removing the 2-acyl group; also acts on other phospholipids by removing a fatty acid from the 2-position; this enzyme has an important role in prostaglandin and leukotriene biosynthesis.
Synonym: lecithinase A, phosphatidase, phosphatidolipase.
(05 Mar 2000)
phospholipase B There are reports that phospholipase B is a mixture of phospholipase A1 and phospholipase A2.
See: lysophospholipase.
(05 Mar 2000)
phospholipase c <enzyme> An enzyme found in the alpha-toxin of clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the formation of 1,2-diacylglycerol and a phosphorylated nitrogenous base such as choline.
Chemical name: Phosphatidylcholine cholinephosphohydrolase
Registry number: EC 3.1.4.3
(12 Dec 1998)
phospholipase d <enzyme> An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyses transphosphatidylation reactions.
Chemical name: Phosphatidylcholine phosphatidohydrolase
Registry number: EC 3.1.4.4
(12 Dec 1998)
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  • Phosphoglycerate Mutase - 새창 An enzyme that catalyzes the conversion of 2-phospho-D-glycerate to 3-phospho-D-glycerate. EC 5.4.2.1.
    Synonyms : Phosphoglycerate Phosphomutase, Mutase, Phosphoglycerate, Phosphomutase, Phosphoglycerate
  • Phospholipase C - 새창 An enzyme found in the alpha-toxin of Clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the formation of 1,2-diacylglycerol and a phosphorylated nitrogenous base such as choline. EC 3.1.4.3.
    Synonyms : alpha Toxin
  • Phospholipase C gamma - 새창 A phospholipase C that is activated in response to growth factor stimulation and TYROSINE phosphorylation. Isoforms of this enzyme are critical for the generation of CALCIUM signals in HEMATOPOIETIC SYSTEMS in response to the stimulation of immune receptors.
    Synonyms : PLC gamma1, PLC-gamma, PLC-gamma 2, PLC-gamma D, PLCgamma2, Phospholipase C gamma 1, Phospholipase C gamma 2, Phospholipase C gamma D, Phospholipase C gamma1, Phospholipase C gamma2, Phospholipase C gammaD, PLC gamma, PLC gamma 2, PLC gamma D
  • Phospholipase D - 새창 An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyzes transphosphatidylation reactions. EC 3.1.4.4.
    Synonyms : Phosphatidylcholine Phosphohydrolase
  • Phospholipases - 새창 A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
    Synonyms : Lecithinase, Phospholipase
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phosgene chemical formula COCl 2 , phosgene is a very toxic gas with a TLV of 0.1ppm. Phosgene has a moldy, hay like odor and is irritating. Phosgene is a reaction product that can form during chlorinated furnace cleans if sufficient oxygen isn't present.
출처: www.icknowledge.com/glossary/p.html
phosgene Carbonyl chloride; a colorless liquid below 8.2
출처: www.nbc-med.org/SiteContent/MedRef/OnlineRef/Field...
phosphoglycerate A three-carbon molecule formed when carbon dioxide is added to ribulose biphosphate (RuBP) during the dark reaction of photosynthesis (Calvin, or Calvin-Benson Cycle). PGA is converted to PGAL, using ATP and NADPH.
출처: www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBook...
phosphate S are salts of phosphoric acid, distributed throughout the body. Inorganic phosphates occur chiefly in the skeleton in association with calcium, where they play a role in the mineralization of bone, and in body fluids, where they play a role in the mineralization of bone, and in body fluids, where they play a role in the regulation of acid/base balance.
출처: www.springboard4health.com/notebook/dict_p.html
phosphorescence Property held by some materials of absorbing light of one wavelength and emitting it as light of a different wavelength.
출처: www.startphoto.com/learn/glossary/glossary_ph-pn.h...
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