para-amino salicylic acid
| NAD(p)h dehydrogenase (quinone) | <enzyme> A flavoprotein that reversibly catalyses the oxidation of NADH or NADPH by various quinones and oxidation-reduction dyes. Since the enzyme is a part of the mitochondrial respiratory chain, defects or deficiencies of this enzyme are an important cause of neurological diseases such as parkinsonism. It may have a protective effect against cancer caused by quinones or their metabolic precursors. The enzyme is inhibited by dicoumarol, capsaicin, and caffeine. Chemical name: NAD(P)H:(quinone-acceptor) oxidoreductase Registry number: EC 1.6.99.2 (12 Dec 1998) |
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| strombine dehydrogenase | <enzyme> Catalyses reductive elimination between pyruvate and glycine producing 2-methyliminodiacetic acid (strombine) Registry number: EC 1.5.1.- (26 Jun 1999) |
| nicotine dehydrogenase | <enzyme> Mo-pterin-fe-s cluster- and fad-dependent enzyme composed of 3 unequal polypeptides; catalyses the conversion of nicotine, acceptor, and water to (s)-6-hydroxynicotine and reduced acceptor Registry number: EC 1.5.99.4 (26 Jun 1999) |
| nitrilotriacetate dehydrogenase | <enzyme> From a denitrifying proteobacteria; does not use oxygen; forms iminodiacetate and glyoxylate; requires phenazine methosulfate as electron carrier Registry number: EC 1.7.99.- Synonym: nta dehydrogenase (26 Jun 1999) |
| nitrite dehydrogenase | <enzyme> Nitrobacter enzyme oxidises nitrite to nitrate with reduction of o2 to water by intermolecular oxygen atom transfer; not the same as nitrate reductase Registry number: EC 1.7.3.- (26 Jun 1999) |
| N-methylalanine dehydrogenase | <enzyme> Methylamine, pyruvate, NADPH and h+ yield n-methylalanine, nadp+ and h2o; analogous to EC 1.4.1.1 Registry number: EC 1.4.1.- (26 Jun 1999) |
| succinate dehydrogenase | <enzyme> Registry number: EC 1.3.99.1 (12 Dec 1998) |
| N-succinylglutamate 5-saemialdehyde dehydrogenase | <enzyme> Catalyses conversion of n-succinylglutamate saemialdehyde to n-succinylglutamate; member of catabolic arginine succinyltransferase pathway; isolated from pseudomonas aeruginosa; genbank af011922 Registry number: EC 1.2.1.- Synonym: arud gene product, sgsd enzyme (26 Jun 1999) |
| D-2-hydroxyacid dehydrogenase | <enzyme> Substrate may be a specific hydroxy acid; enzyme from trypanosoma cruzi; has been sequenced; genbank u31175 (ddh gene product) Registry number: EC 1.1.99.6 Synonym: alpha-hydroxyacid dehydrogenase, ddh gene product, staphylococcus aureus, d-lactate dehydrogenase (nad) (26 Jun 1999) |
| sulfide dehydrogenase | <enzyme> From bacteria Registry number: EC 1.8.2.- Synonym: flavocytochrome c, soxb protein, soxb gene product (26 Jun 1999) |
| D-arabinose dehydrogenase | <enzyme> See also record for l-arabinose dehydrogenase (EC 1.1.1.46) Registry number: EC 1.1.1.116 (26 Jun 1999) |
| deficiency, glucose-6-phosphate dehydrogenase | Deficiency of G6PD is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anaemia due to breakup of their red blood cells when they are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics or sulfones, naphthalene moth balls, or fava beans. (12 Dec 1998) |
| dehydrogenase | <enzyme> Enzyme that oxidizes a substrate by transferring hydrogen to an acceptor that is either NAD/NADP or a flavin enzyme. (18 Nov 1997) |
| delta-1-piperideine-6-carboxylate dehydrogenase | <enzyme> From streptomyces clavuligerus and other cephamycin c-producing actinomycetes; converts delta-1-piperideine-6-carboxylate to alpha-aminoadipic acid Registry number: EC 1.5.1.- Synonym: p6c dehydrogenase (26 Jun 1999) |
| delta(5)-3 beta-hydroxysteroid dehydrogenase | <enzyme> Converts dehydroepiandrosterone to delta-4-androstene-3,17-dione Registry number: EC 1.1.1.- Synonym: dbhdase, 3 beta-hydroxy-5-ene-steroid dehydrogenase, steroid-delta(5)-3-ol dehydrogenase (26 Jun 1999) |