| leukotriene A4 hydrolase | <enzyme> Catalyses hydrolysis of leukotriene a4 to leukotriene b4; mw 68,000-70,000 Registry number: EC 3.3.2.- Synonym: leukotriene a4 aminopeptidase (26 Jun 1999) |
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| leukotriene b4 | <chemical> (s-(r*,s*-(e,z,e,z)))-5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid. The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centreed free radicals, arachidonic acid release, and metabolism). Chemical name: 6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))- (12 Dec 1998) |
| leukotriene B4 12-hydroxydehydrogenase | <enzyme> Catalyses the oxidation of leukotriene b4 to 12-oxoleukotriene b4 Registry number: EC 1.1.1.- Synonym: ltb4 12-hydroxydehydrogenase, ltb(4) 12-hydroxydehydrogenase (26 Jun 1999) |
| leukotriene B4 6-isomerase | <enzyme> From rat kidney homogenates Registry number: EC 5.2.- (26 Jun 1999) |
| leukotriene B4 reductase | <enzyme> Converts leukotriene b4 (5s,12r-dihydroxyeicosoletra-6,8,10,14-enoic acid) to dihydro ltb4 (5s,12r-10,11-dihydroeicosatri-6,8,14-enoic acid), requires NADPH, ca and mg Registry number: EC 1.3.1.- (26 Jun 1999) |
| leukotriene c4 | <chemical> (r-(r*,s*-(e,e,z,z))))-n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-n-l-gamma-glutamyl-l-cysteinyl)glycine. The conjugation product of leukotriene a4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitised lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. Chemical name: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))- (12 Dec 1998) |
| leukotriene d4 | <chemical> (r-(r*,s*-(e,e,z,z)))-n-(s-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-l-cysteinyl)glycine. One of the biologically active principles of srs-a. It is generated from leukotriene c4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. Chemical name: Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))- (12 Dec 1998) |
| leukotriene D4 dipeptidase | <enzyme> Converts leukotriene d4 to leukotriene e4 Registry number: EC 3.4.13.- Synonym: ld4 dipeptidase (26 Jun 1999) |
| leukotriene e4 | <chemical> (5s-(5r*,6s*(s*),7e,9e,11z,14z))-6-((2-amino-2-carboxyethyl)thio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid. A biologically active principle of srs-a that is formed from leukotriene d4 via a peptidase reaction that removes the glycine residue. The biological actions of lte4 are similar to ltc4 and ltd4. Chemical name: 7,9,11,14-Eicosatetraenoic acid, 6-((2-amino-2-carboxyethyl)thio)-5-hydroxy-, (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))- (12 Dec 1998) |
| leukotriene-C4 synthase | <enzyme> From particulate fraction of rat basophil leukaemia homogenates; not sensitive to inhibitors of most soluble glutathione s-transferases Registry number: EC 2.5.1.37 Synonym: leukotriene c synthase, leukotriene a4-glutathione s-leukotrienyltransferase, leukotriene c4 synthetase, glutathione s-transferase II, gst-ii (26 Jun 1999) |
| leukotrienes | A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system. (12 Dec 1998) |
| Leukovirus | A former genus composed of the RNA tumour viruses now included in the family Retroviridae. (05 Mar 2000) |
| leukocytosis |
An increase above the upper limit of normal in the concentration of blood leukocytes (white cells).
출처: www.cllinfo.com/Glossary/glossary_L.html
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| leukocyte alkaline phosphatase |
This neutrophil enzyme is markedly decreased in its activity in patients with chronic myelogenous leukemia. It had been used as a laboratory test to distinguish the increase in white blood cell count in chronic myelogenous leukemia from other causes of leukocytosis. The test is of historical interest and has been replaced by measurement of BCR gene rearrangement, a more specific alteration present in virtually all patients with chronic myelogenous leukemia.
출처: www.cllinfo.com/Glossary/glossary_L.html
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| leuko- |
Leukoplast hat mehrere Bedeutungen#Leukoplast (umgangssprachlich: Leuko) ist der Markenname f? einen medizinisches Klebeband#Die Leukoplasten sind eine Gruppe von Organellen in pflanzlichen Zellen. Zusammen mit den Chromoplasten und den Chloroplasten geh?en sie zu den Plastiden. Leukoplasten sind farblos, in ihnen findet also keine Photosynthese statt. ...
출처: de.wikipedia.org/wiki/Leuko
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| leukocytosis |
total white blood cell count greater than 11,000 per cubic millimeter. Leukocytosis refers specifically to elevation in the number of polymorphonuclear leukocytes, which make up the majority of white blood cells.
출처: www.brooksidepress.org/Products/OperationalMedicin...
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| leukodystrophy |
A group of genetic disorders characterized by the imperfect development or maintenance of myelin. Diseases in this class include adrenoleukodystrophy, Alexander disease, Canavan disease, Krabbe disease, metachromatic leukodystrophy, Pelizaeus-Merzbacher disease, Refsum disease, and phenylketonuria.
출처: www.myelin.org/glossary.htm
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