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hypoxia-i. see under H.
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hypoxia-ischemia the changes occurring in tissues when the blood supply is cut off, particularly in a fetus or infant with asphyxia; see also hypoxic-ischemic encephalopathy under encephalopathy.
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hypoxic e. encephalopathy caused by hypoxia from either decreased rate of blood flow or decreased oxygen content of arterial blood; symptoms in mild cases include intellectual, visual, and motor disturbances. Severe cases, such as with cardiac arrest or blocking of the airways, can cause permanent damage within five minutes. Called also anoxic e.
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hypoxic h. that due to insufficient oxygen reaching the blood, as at decreased barometric pressures at high altitudes. Cf. anoxic anoxia.
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hypoxic-ischemic e. encephalopathy resulting from asphyxia. In infants presumed to have suffered prenatal or perinatal asphyxia, common symptoms are lethargy, feeding difficulties, and convulsions; serious cases may involve necrosis of neurons in the brain with psychomotor retardation and spastic motor deficits such as cerebral palsy. In adults, syndromes range from cortical blindness to irreversible coma.
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