| glycerol-3-phosphate O |
[EC 2.3.1.15] an enzyme of the transferase class that catalyzes the transfer of an acyl group to glycerol 3-phosphate from an acyl CoA with a chain longer than ten carbons, yielding a lysophosphatidate. The reaction is a step in the synthesis of triglycerides and phosphatidates, and the enzyme also catalyzes the addition of a second acyl group to the lysophosphatidate to form a phosphatidate.
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| glycerol-3-phosphate dehydrogenase |
[EC 1.1.99.5] an enzyme of the oxidoreductase class that catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate. In mitochondria of striated muscle and of nervous tissue, the enzyme contains iron and the acceptor is FAD. The dihydroxyacetone phosphate formed can cross into the cytosol, where glycerol-3-phosphate dehydrogenase (NAD+) catalyzes its reduction via electrons from NADH, regenerating glycerol 3-phosphate. See also glycerol phosphate shuttle, under shuttle.
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| glycerol-3-phosphate dehydrogenase (NAD+) |
[EC 1.1.1.8] a cytosolic enzyme of the oxidoreductase class that catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate, with NAD+ as the electron acceptor. NADH formed from NAD+ by other reactions displaces the equilibrium, producing glycerol 3-phosphate and the oxidized nucleotide NAD+. The glycerol phosphate produced can cross into the mitochondria, where it is reoxidized by glycerol-3-phosphate dehydrogenase, regenerating dihydroxyacetone phosphate and donating electrons to FAD. See also glycerol phosphate shuttle, under shuttle.
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| glyceroluria |
excretion of glycerol in the urine, such as in hyperglycerolemia.
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| glycerone |
formal, seldom used, term for dihydroxyacetone.
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