| tapetoretinal degeneration | A hereditary disorder of the retina mainly affecting photoreceptors and retinal pigment epithelium; a miscellaneous category including Friedreich's ataxia, Refsum's disease, and abetalipoproteinaemia. Synonym: primary pigmentary degeneration of retina. (05 Mar 2000) |
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| Terrien's marginal degeneration | A form of marginal corneal degeneration. (05 Mar 2000) |
| ectatic marginal degeneration of cornea | Bilateral opacification and vascularization of the periphery of the cornea, progressing to formation of a gutter and ectasia. Synonym: ectatic marginal degeneration of cornea. (05 Mar 2000) |
| elastoid degeneration | 1. Degenerative change in elastic tissue. 2. Degeneration of collagen fibres, with altered staining properties resembling elastic tissue, or formation by fibroblast-activated ultraviolet or mast cell mediators of abnormal fibres. Synonym: elastoid degeneration, elastotic degeneration. (05 Mar 2000) |
| elastotic degeneration | 1. Degenerative change in elastic tissue. 2. Degeneration of collagen fibres, with altered staining properties resembling elastic tissue, or formation by fibroblast-activated ultraviolet or mast cell mediators of abnormal fibres. Synonym: elastoid degeneration, elastotic degeneration. (05 Mar 2000) |
| transsynaptic degeneration | An atrophy of nerve cells following damage to the axons that make synaptic connection with them; noted especially in the lateral geniculate body. Synonym: transneuronal atrophy, transsynaptic chromatolysis. (05 Mar 2000) |
| Turck's degeneration | Degeneration of a nerve fibre and its sheath distal to the point of injury or section of the axon; usually applied to degeneration within the central nervous system. (05 Mar 2000) |
| familial pseudoinflammatory macular degeneration | Macular degeneration that occurs during the fifth decade of life, with sudden development of a central scotoma in one eye followed rapidly by a similar lesion in the opposite eye; autosomal dominant inheritance. Synonym: Sorsby's macular degeneration. (05 Mar 2000) |
| fascicular degeneration | Muscular degeneration due to loss of motor neurons in the spinal cord or brainstem. (05 Mar 2000) |
| Zenker's degeneration | A form of severe hyaline degeneration or necrosis in skeletal muscle, occurring in severe infections. Synonym: waxy degeneration, Zenker's necrosis. (05 Mar 2000) |
| Kuhnt-Junius degeneration | An obsolete eponym for disciform degeneration. Synonym: Kuhnt-Junius disease. (05 Mar 2000) |
| fibrinous degeneration | A process resulting in poorly defined, deeply acidophilic, homogeneous refractile deposits with some staining reactions that resemble fibrin, occurring in connective tissue, blood vessel walls, and other sites. (05 Mar 2000) |
| fibrous degeneration | Not a degeneration per se, but rather a reparative process; cells and foci of tissue previously affected with degenerative processes, and necrosis, are replaced by cellular fibrous tissue. (05 Mar 2000) |
| lenticular progressive degeneration | <gastroenterology, neurology> An inherited (autosomal recessive) disorder where there is excessive quantities of copper in the tissues, particularly the liver and central nervous system. Wilson's disease causes the body to absorb and retain copper. The copper deposits in the liver, brain, kidneys and eyes. Complications include dementia and liver failure. Symptoms include jaundice, vomiting, tremors, weakness and slow stiff movements. Blood tests show serum ceruloplasmin is low. Medications are given to remove the excess copper from the body. Even with life-long treatment, disabling (and life-threatening) side effects are common. Inheritance: autosomal recessive. (27 Sep 1997) |
| liquefaction degeneration | Necrosis with softening, as in ischemic brain tissue, dissolution of the basal epidermal layer by necrosis of scattered cells with oedema, observed in lichen planus, lupus erythematosus, and other dermatologic conditions. (05 Mar 2000) |