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depolarize to reduce toward a nonpolarized condition; to deprive of polarity. See depolarization.
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depolarizer 1. a chemical agent placed in a galvanic cell for reducing the polarization of an electrode.  2. a substance that reduces the voltage across a biological membrane.  3. a muscle relaxant that produces striated muscle paralysis by altering the electrical state of the muscle receptor, thus blocking muscle response to nerve impulse.
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depolarizing neuromuscular blocking a. a nicotinic agonist that blocks neural transmission at the myoneural junction by binding to the nicotinic receptors of the motor end plate to produce prolonged depolarization of the postsynaptic membrane.
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depolymerize to cause to undergo depolymerization.
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depot i. injection of a medication that stays in a local area (a depot) and is distributed slowly into the body; absorption is often kept slow by mixing the medication with a suitable excipient.
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