| SCID | Structured Clinical Interview for DSM III |
|---|---|
| SCID-P | Structured Clinical Interview for DSM-III-R Patient version |
| SCID II | Structured Clinical Interview for DSM-III-R Personality Disorders |
| SIDP | Structured Interview for DSM III Personality Disorders |
| TAT | Thrombin antithrombin III complex |
| heteromeric peptide | A peptide which, on hydrolysis, yields substances other than amino acids in addition to amino acids; e.g., pteroylglutamic acid. (05 Mar 2000) |
|---|---|
| homodetic peptide | A peptide in which all of the covalent linkages between the constituent amino acids are peptide bonds; e.g., bradykinin. Origin: homo-+ G. Detos, bound, fr. Deo, to bind, + -ic (05 Mar 2000) |
| homomeric peptide | A peptide which, on hydrolysis, yields only amino acids; e.g., glutathione, A peptide which consists of only one particular amino acid; e.g., alanylalanylalanine. (05 Mar 2000) |
| sigma peptide | A peptide with one end bonded to a point within the chain, usually by means of the disulfide group of a cystine residue, so that only one end of the peptide is free; so called since the peptide chain has then the rough shape of the Greek letter sigma; e.g., oxytocin. (05 Mar 2000) |
| signal peptide | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
| signal peptide p25-subunit IV cytochrome oxidase | <chemical> Similar in action to melittin Synonym: p25 presequence peptide-cytochrome oxidase, pre-ctox p25 (26 Jun 1999) |
| non-ribosomal peptide synthase | <enzyme> Nrp - non-ribosomal peptide/polyketide; locus nrp is mutated in a swarming-defective proteus mirabilis strain; 249 amino acid residues, mw 29.7 kD; amimo acid sequence given in first source Registry number: EC 6.3.2.- Synonym: nrpg protein, nrpg gene product (26 Jun 1999) |
| delta sleep-inducing peptide | <chemical> A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal. Chemical name: Delta sleep-inducing peptide (12 Dec 1998) |
| diabetes related peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| insulin c-peptide | <investigation> A blood test which measures the amount of C-peptide in the blood. C-peptide is a byproduct of normal insulin production by the beta cells in the pancreas. Normal values are 0.5 to 3.0 ng/ml. Normal levels indicate that the body is still producing its own insulin. Low levels indicate that the pancreas is producing little or no insulin. Elevations can be seen in cases of insulinomas and islet of Langerhans tumours. (27 Sep 1997) |
| insulin-stimulating peptide | <chemical> 71-amino acid containing peptide; corresponds to residues 115-143 and 144-184 of bovine serum albumin with the exception of a tyrosine insertion between residues 155 and 156; consists of two chains with mw 5000 and 3400 for each chain Synonym: h-isp, insulin-stimulating protein (05 Dec 1998) |
| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| eosinophil chemotactic peptide | <protein> Tetrapeptides (of which two are identified: VGSE and AGSE) released by mast cells and that are said to both attract and activate eosinophils. (18 Nov 1997) |
| UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase | <enzyme> Responsible for the addition of o-linked n-acetylglucosamine to proteins Registry number: EC 2.4.1.- Synonym: udp-glcnac-peptide-glcnac-transferase, glcnac transferase (26 Jun 1999) |
| formyl peptide | <biochemistry> Informal term for small peptides with a formylated N terminal methionine and usually a hydrophobic amino acid at the carboxy terminal end (fMetLeuPhe is the most commonly used). These peptides stimulate the motor and secretory activities of leucocytes, particularly neutrophils and monocytes, that have a specific receptor (about 60 kD) of high affinity (Kd approximately 10exp 8M). Leucocytes show chemotaxis towards formyl peptides but the term chemotactic peptides understates the range of activities the molecules will trigger. Thought to be synthetic analogues of bacterial signal sequences though this is unproven. The leucocytes of many animals (e.g. Pig, cow, chicken) do not respond. (18 Nov 1997) |