| beta-sulfinylpyruvic acid | <biochemistry> An intermediate product of l-cysteine catabolism in mammalian tissue. Structure: HO2S-CH2-CO-COOH (05 Mar 2000) |
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| Beta tests | <psychiatry> A set of pictorially administered mental tests first used in the United States Army in 1917-1918 to determine the relative mental ability of recruits who were illiterate or deficient in reading and writing English, the instructions being given in signs and the test material's pictorial in characters; distinguished from the Army Alpha tests, which were administered at the same time to literate recruits. Synonym: Army Beta tests. (05 Mar 2000) |
| beta thalassaemia | <haematology> Thalassaemia due to one of two or more genes that depress (partially or completely) synthesis of beta-globin chains by the chromosome bearing the abnormal gene. Heterozygous state (A2 t.): thalassaemia minor with Hb A2 increased, Hb F normal or variably increased, Hb A normal or slightly reduced. Homozygous state: thalassaemia major with Hb A reduced to very low but variable levels, Hb F very high level. A disorder characterised by reduced synthesis of the beta chains of haemoglobin. There is retardation of haemoglobin a synthesis in the heterozygous form (thalassaemia minor), which is asymptomatic, while in the homozygous form (thalassaemia major, cooley's anaemia, mediterranean anaemia, erythroblastic anaemia), which can result in severe complications and even death, haemoglobin a synthesis is absent. (05 Mar 2000) |
| beta-thionase | <enzyme> A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyses the reaction of homocysteine with serine to form cystathionine with the elimination of water. Chemical name: L-Serine hydro-lyase (adding homocysteine) Registry number: EC 4.2.1.22 (12 Dec 1998) |
| beta-thromboglobulin | <haematology> A platelet-specific protein which is released when platelets aggregate. Elevated plasma levels have been reported after deep venous thrombosis, preeclampsia, myocardial infarction with mural thrombosis, and myeloproliferative disorders. Measurement of beta-thromboglobulin in biological fluids by radioimmunoassay is used for the diagnosis and assessment of progress of thromboembolic disorders. (12 Dec 1998) |
| beta-tocopherol | 5,8-Dimethyltocol;a lower homolog of alpha-tocopherol, that contains one less methyl group in the aromatic nucleus and is less active biologically; accompanies alpha-T and gamma-beta-tocopherol (05 Mar 2000) |
| beta-tyrosinase | <enzyme> An enzyme that catalyses the cleavage of tyrosine to phenol, pyruvate, and ammonia. It is a pyridoxal phosphate protein. The enzyme also forms pyruvate from d-tyrosine, l-cysteine, s-methyl-l-cysteine, l-serine, and d-serine, although at a slower rate. Chemical name: L-Tyrosine phenol-lyase (deaminating) Registry number: EC 4.1.99.2 (12 Dec 1998) |
| beta-ureidopropionase | <enzyme> Chemical name: n-carbamoyl-beta-alanine amidohydrolase Registry number: EC 3.5.1.6 Synonym: n-carbamoyl beta-alanine amidohydrolase (26 Jun 1999) |
| beta wave | <neurology> Brain waves in the electroencephalogram which have a frequency of 18 to 30 per second. They are typical during periods of intense activity of the nervous system, and occur principally in the parietal and frontal regions. (12 Dec 1998) |
| broad beta disease | Hyperlipoproteinaemia characterised by increased plasma levels of LDL, beta-lipoproteins, pre-beta-lipoproteins, cholesterol, phospholipids, and triglycerides; hypertriglyceridemia induced by a high carbohydrate diet, and glucose tolerance is abnormal; frequent eruptive xanthomas and atheromatosis, particularly coronary artery disease; biochemical defect lies in apolipoproteins; there are many varieties. Synonym: carbohydrate-induced hyperlipaemia, dysbetalipoproteinaemia, familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemia, familial hypercholesterolaemia with hyperlipaemia. (05 Mar 2000) |
| galactosylxylosylprotein 3-beta-galactosyltransferase | <enzyme> Catalyses the reaction of udpgalactose and 4-beta-d-(galactosyl-o-beta-d-xylosylprotein to yield udp and 3-beta-d-galactosyl-o-beta-d-xylosylprotein Registry number: EC 2.4.1.134 Synonym: galactosyltransferase II, (26 Jun 1999) |
| mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase | <enzyme> Transfers n-acetylglucosamine from udp-glcnac in beta 1-4 linkage to the d-mannose residue of glcnac beta 1-6 (glcnac beta 1-2)man alpha-r where r is 1-6 man beta-(ch2)8cooch3 on methyl; model for asparagine linked oligosaccharide Registry number: EC 2.4.1.- Synonym: n-acetylglucosaminyltransferase vi (26 Jun 1999) |
| mannosyl-glycoprotein endo-beta-n-acetylglucosaminidase | <enzyme> A group of related enzymes responsible for the endohydrolysis of the di-n-acetylchitobiosyl unit in high-mannose-content glycopeptides and glycoproteins. Chemical name: Glycopeptide-D-mannosyl-N(4)-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase Registry number: EC 3.2.1.96 (12 Dec 1998) |
| gene rearrangement, beta-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the beta-chain of antigen receptors. (12 Dec 1998) |
| genes, T-cell receptor beta | DNA sequences encoding the beta chain of the T-cell receptor. The genomic organization of the tcr beta genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |