| autoimmune g. |
an autoimmune disorder of the stomach resulting from the presence of circulating autoantibodies against the parietal cells, characterized by inflammation and atrophy of the mucosa of the body of the stomach, with replacement of normal mucosa by antral, pseudopyloric, and intestinal metaplasia. Destruction of the mucosal glands results in achlorhydria and a decrease in production of intrinsic factor, in severe cases leading to failure of vitamin B12 absorption and pernicious anemia. Called also diffuse corporal atrophic g. and type A g.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| autoimmune h. |
1. an autoimmune disease of the liver, occurring chiefly in females, characterized by circulating autoantibodies and hypergammaglobulinemia and associated with extrahepatic complaints such as malaise, fever, and arthralgia. Type 1 is characterized by antinuclear and anti–smooth muscle antibodies; type 2 is less common and is characterized by antibodies against the microsomal antigen of liver and kidney. 2. chronic active h.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| autoimmune hemolytic a. |
any of a large group of anemias involving autoantibodies against red cell antigens. Those due to warm-reactive antibodies, usually IgG but occasionally IgM or IgA, may be idiopathic or secondary to autoimmune diseases, hematologic neoplasms, viral infections, or immunodeficiency diseases, and usually involve sequestration of sensitized erythrocytes by the spleen. Those due to cold-reactive antibodies, usually IgM but occasionally IgG, include cold agglutinin syndrome and paroxysmal cold hemoglobinuria and usually involve complement-dependent intravascular hemolysis or sequestration of erythrocytes by the liver.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| autoimmune n. |
that caused by autoantibodies against the neutrophils; it may occur in isolation, in association with other autoimmune conditions, or secondary to malignancy, infection, or a drug complication. The most common type is alloimmune neonatal neutropenia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| autoimmune polyendocrine-candidiasis s. |
polyglandular autoimmune s., type I.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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