| Somogyi | Michael, U.S. Biochemist, 1883-1971. See: Somogyi effect, Somogyi method, Somogyi unit. (05 Mar 2000) |
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| Somogyi effect | In diabetes, a rebound phenomenon of reactive hyperglycaemia in response to a preceding period of relative hypoglycaemia that has increased secretion of hyperglycaemic agents (epinephrine, norepinephrine, glucagon, cortisol, and growth hormone); described in diabetic patients given too much insulin who developed unrecognised nocturnal hypoglycaemia that made them hyperglycaemic (suggesting insufficient insulin) when tested the next morning. (05 Mar 2000) |
| Somogyi method | A measure of the level of activity of amylase in blood serum, as analyzed by means of the Somogyi method (the most frequently used procedure); one unit is equivalent to 1 mg of reducing sugar liberated as glucose per 100 ml of serum, when an aliquot of the latter is mixed with a standard starch substrate (plus sodium chloride for maximal activation) and incubated for a standard time; normal range is 80 to 150 unit's, but values are usually not regarded as clinically significant unless they are greater than 200. (05 Mar 2000) |
| Somogyi phenomenon | A rebound phenomenon of reactive hyperglycaemia following a period of relative hypoglycaemia, which may be subclinical and difficult to detect; the hyperglycaemia induces use of more insulin, thus aggravating the problem. Synonym: posthypoglycaemic hyperglycaemia. (05 Mar 2000) |
| Somogyi unit | A measure of the level of activity of amylase in blood serum, as analyzed by means of the Somogyi method (the most frequently used procedure); one unit is equivalent to 1 mg of reducing sugar liberated as glucose per 100 ml of serum, when an aliquot of the latter is mixed with a standard starch substrate (plus sodium chloride for maximal activation) and incubated for a standard time; normal range is 80 to 150 unit's, but values are usually not regarded as clinically significant unless they are greater than 200. (05 Mar 2000) |