| oligo-isomaltosaccharide synthase | <enzyme> Catalyses the formation of alpha-1,6-linked linear oligosaccharides from sucrose; isolated from streptococcus sobrinus Registry number: EC 2.4.1.- Synonym: gtf-s gene product, rgtf-s(3), glucosyltransferase s, glucosyltransferase-s, gtfd gene product (26 Jun 1999) |
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| o-succinylbenzoic acid synthase | <enzyme> E coli enzyme; with shchc synthase catalyses formation of o-succinylbenzoic acid from isochorismic acid and alpha-ketoglutarate in presence of thiamine pyropyrophosphate; succinic saemialdehyde anion is formed by decarboxylation of alpha-ketoglutarate by thiamine pyrophosphate; anion then attacks isochorismic acid, initiating aromatization with elimination of pyruvate and h2o Registry number: EC 4.1.99.- Synonym: ortho-succinylbenzoic acid synthase, osb synthase, 2-succinylbenzoic acid synthase (26 Jun 1999) |
| taxa-4(5),11(12)-diene synthase | <enzyme> Catalyses the cyclization of geranylgeranyl pyrophosphate to taxa-4(5),11(12)-diene, the first step to taxol biosynthesis Registry number: EC 5.- Synonym: taxadiene synthase, taxadiene cyclase (26 Jun 1999) |
| terpene synthase | <enzyme> Acts on dimethylallyl pyrophosphate (pp), geranyl pp, farnesyl pp and geranylgeranyl pp to generate a wide range of terpenoids; genbank y11188 Registry number: EC 2.5.1.- Synonym: ts1 protein, plant, atts1 gene product, (26 Jun 1999) |
| thromboxane-a synthase | <enzyme> An enzyme found predominantly in platelet microsomes. It catalyses the conversion of pgg(2) and pgh(2) (prostaglandin endoperoxides) to thromboxane a2. Chemical name: (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A(2)-isomerase Registry number: EC 5.3.99.5 (12 Dec 1998) |
| thymidylate synthase | <enzyme> An enzyme of the transferase class that catalyses the reaction 5,10-methylenetetrahydrofolate and dump to dihydrofolate and dtmp in the synthesis of thymidine triphosphate. Chemical name: 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase Registry number: EC 2.1.1.45 (12 Dec 1998) |
| thymidylate synthase-dihydrofolate reductase | <chemical> Bifunctional multienzyme complex purified from leishmania major Synonym: ts-dhfr, dhfr-ts (26 Jun 1999) |
| ectoine synthase | <enzyme> Catalyses cyclic condensation of n(gamma)-l-2,4-diaminobutyric acid to yield l-ectoine Registry number: EC 4.2.1.- Synonym: ectc gene product (26 Jun 1999) |
| endothelium-derived growth factor synthase | <enzyme> Converts l-arginine to a smooth muscle relaxing factor and stimulates the formation of cyclic-GMP Registry number: EC 1.5.1.- Synonym: edrf synthase (26 Jun 1999) |
| trehalose synthase | <enzyme> Catalyses the conversion of maltose into alpha,alpha-trehalose by intramolecular transglucosylation; mw about 62 kD; genbank d78198 Registry number: EC 2.4.1.- Synonym: tres gene product, tres enzyme (26 Jun 1999) |
| tRNA 2-selenouridine synthase | <enzyme> Catalyses the conversion of a 5-methylaminomethyl-2-thiouridine in trna to 5-methylaminomethyl-2-selenouridine Registry number: EC 2.8.1.- (26 Jun 1999) |
| tryptophan synthase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
| farnesylgeranyl diphosphate synthase | <enzyme> A prenyltransferase which synthesises c25-prenyl diphosphate; distinct from geranylgeranyl diphosphate synthase (EC 2.5.1.29); can use geranylgeranyl diphosphate as a substrate Registry number: EC 2.5.1.- Synonym: fgpp synthase (26 Jun 1999) |
| UMP synthase | Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. Synonym: UMP synthase, uridine 5'-monophosphate. Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria. (05 Mar 2000) |
| fatty acid 2-chloroethyl ester synthase | <enzyme> Catalyses the formation of 2-chloroethyl esters of long-chain fatty acids; localised in the microsomal fraction of rat liver Registry number: EC 2.3.1.- Synonym: facees, 2-chloroethyl ester synthase (26 Jun 1999) |