Loss of Heterozygosity - ț̢
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal hemizygosity. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted. When this occurs at a tumor suppressor gene locus where one of the alleles is already abnormal, it can result in neoplastic transformation (CELL TRANSFORMATION, NEOPLASTIC).
Synonyms : Allelic Losses, Heterozygosity Loss
Lotus - ț̢
A plant genus of the family FABACEAE. This genus was formerly known as Tetragonolobus. The common name of lotus is also used for NYMPHAEA and NELUMBO.
Synonyms :
Loudness Perception - ț̢
The perceived attribute of a sound which corresponds to the physical attribute of intensity.