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ionophore <chemistry> A molecule that allows ions to cross lipid bilayers. There are two classes: carriers and channels. Carriers, like valinomycin, form cage like structures around specific ions, diffusing freely through the hydrophobic regions of the bilayer. Channels, like gramicidin, form continuous aqueous pores through the bilayer, allowing ions to diffuse through.
See: ion channels.
(18 Nov 1997)
ionophores Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
(12 Dec 1998)
ionophoresis Synonym: electrophoresis.
Origin: ion + G. Phoresis, a carrying
(05 Mar 2000)
ionophoretic Relating to electrophoresis, as an electrophoretic separation.
Synonym: ionophoretic.
(05 Mar 2000)
ionosphere <radiobiology> Ionised region of the upper earth atmosphere, which behaves like a plasma, including reflection of AM radio waves and generation of auroral glows.
(09 Oct 1997)
ions Atoms or radicals having a charge of positive (cation) or negative (anion) electricity owing to the loss (positive) or gain (negative) of one or more electrons.
(12 Dec 1998)
iontophoresis Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow.
(18 Nov 1997)
iontophoretic Relating to iontophoresis.
(05 Mar 2000)
iontotherapy Movement of ions as a result of an applied electric field. For example the delivery of a charged molecule from the end of a micropipette without hydraulic flow.
(18 Nov 1997)
iopamidol <chemical> An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures. Its non-ionic, water-soluble properties result in optimal imaging and reduced toxicity.
Pharmacological action: contrast media.
Chemical name: 1,3-Benzenedicarboxamide, N,N'-bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-
(12 Dec 1998)
iopanoic acid <chemical> 3-amino-alpha-ethyl-2,4,6-triiodobenzenepropanoic acid. Radiopaque medium used as diagnostic aid.
Pharmacological action: contrast media.
Chemical name: Benzenepropanoic acid, 3-amino-alpha-ethyl-2,4,6-triiodo-
(12 Dec 1998)
iopentol N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl) acetamido]-2,4,6-triiodoisophthalamide;a nonionic, monomeric, low osmolar radiographic contrast medium for intravenous urography or angiography.
(05 Mar 2000)
iophendylate <chemical> Ethyl-10(p-iodophenyl)undecylate. A mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization.
Pharmacological action: contrast media.
Chemical name: Benzenedecanoic acid, 4-iodo-iota-methyl-, ethyl ester
(12 Dec 1998)
iophenoic acid Alpha-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid;a radiographic contrast medium; formerly used for oral cholecystography.
Synonym: iophenoic acid.
(05 Mar 2000)
iophenoxic acid Alpha-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid;a radiographic contrast medium; formerly used for oral cholecystography.
Synonym: iophenoic acid.
(05 Mar 2000)
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