| genes, structural, neoplasm | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of neoplastic cells. (12 Dec 1998) |
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| genes, structural, plant | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of plant cells. (12 Dec 1998) |
| genes, structural, protozoan | DNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of protozoan cells. (12 Dec 1998) |
| genes, structural, viral | DNA or RNA sequences that code for RNA and for the proteins required for the enzymatic and structural function of viral cells. (12 Dec 1998) |
| genes, suppressor | Genes that inhibit expression of a previous mutation. They allow the wild-type phenotype to be wholly or partially restored. (12 Dec 1998) |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
| genes, switch | Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realised) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation. (12 Dec 1998) |
| genes, synthetic | Biologically functional sequences of DNA chemically synthesised in vitro. (12 Dec 1998) |
| genes, tat | DNA sequences that form the coding region for the protein responsible for trans-activation of transcription (tat) in human immunodeficiency virus (HIV). (12 Dec 1998) |
| genes, T-cell receptor | DNA sequences, in cells of the t-lymphocyte lineage, that code for T-cell receptors. The tcr genes are formed by somatic rearrangement (see gene rearrangement, t-lymphocyte and its children) of germline gene segments, and resemble ig genes in their mechanisms of diversity generation and expression. (12 Dec 1998) |
| genes, T-cell receptor alpha | DNA sequences encoding the alpha chain of the T-cell receptor. The genomic organization of the tcr alpha genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| genes, T-cell receptor beta | DNA sequences encoding the beta chain of the T-cell receptor. The genomic organization of the tcr beta genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| genes, T-cell receptor delta | DNA sequences encoding the delta chain of the T-cell receptor. The delta-chain locus is located entirely within the alpha-chain locus. (12 Dec 1998) |
| genes, T-cell receptor gamma | DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organised similarly to the tcr beta-chain locus. (12 Dec 1998) |
| genes, vif | DNA sequences that form the coding region for the vif (virion infectivity factor) protein that is important for the generation of infectious virions in human immunodeficiency virus (HIV). The former name of this gene was sor (short open reading frame). (12 Dec 1998) |