| DNAh gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes some of the components of the DNA Polymerase III protein, an enzyme which plays an important role in DNA replication. (09 Oct 1997) |
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| DNAi gene | <molecular biology> A gene that makes a protein which plays a role in DNA replication. (09 Oct 1997) |
| DNAj gene | <molecular biology> A gene found in the bacteria Escherichia coli which helps the bacteria survive at high temperatures. It also plays an important role in the replication of the DNA of bacteriophage lambda. It is closely linked with the DNAK gene. (09 Oct 1997) |
| DNAk gene | <molecular biology> A gene found in the bacteria Escherichia coli which helps the bacteria survive at high temperatures. It also is important in the replication of the DNA of bacteriophage lambda. It is closely linked with the DNAJ gene. (09 Oct 1997) |
| DNAl gene | <molecular biology> A type of DNA gene which has not been described. (09 Oct 1997) |
| DNAq gene | <molecular biology> A gene found in the bacteria Escherichia coli which makes some of the components of the DNA Polymerase III protein, an enzyme with an important role in DNA replication. (09 Oct 1997) |
| DNAse | <enzyme> An endonuclease with preference for DNA. Pancreatic DNAse I yields di and oligo nucleotide 5_ phosphates, pancreatic DNAse II yields 3_ phosphates. In chromatin, the sensitivity of DNA to digestion by DNAse I depends on its state of organisation, transcriptionally active genes being much more sensitive than inactive genes. Acronym: DNAase (10 Nov 1998) |
| DNAse footprinting | <molecular biology> A lab technique used to find out which segments of a DNA molecule are protected by DNA-binding proteins from attack by endonuclease enzymes, which break down DNA into smaller fragments by cleaving its phosphodiester bonds. The technique does this with gel electrophoresis to find out which parts of the DNA have sites for proteins to attach to them, by comparing DNA which has been in the presence of DNA-binding proteins with DNA that is pure. (09 Oct 1997) |
| DNAse i | A type of endonuclease, or enzyme that breaks down DNA molecules at their phosphodiester bonds. It is found in large quantities in the pancreas. (09 Oct 1997) |
| DNAse i hypersensitivity site | <molecular biology> A site on a DNA molecule that is especially prone to being cut apart by the endonuclease enzyme DNase I, which breaks down DNA into smaller fragments by cleaving phosphodiester bonds. These sites tend to be near active genes, which are regularly transcribed. (09 Oct 1997) |
| DNAse i sensitivity | <molecular biology> The likelihood that a particular DNA segment will be attacked by the endonuclease enzyme DNase I, which breaks down DNA into smaller fragments by cleaving its phosphodiester bonds. DNA segments which contain active genes that are regularly transcribed are more prone to being cut apart by DNase I than inactivated genes, because the inactivated genes are generally within condensed regions of the chromosome, while the active genes are in more open configurations for easy access for transcription. (09 Oct 1997) |
| DNAt gene | <molecular biology> A gene that helps dismantle the replication complex (the combination of proteins and enzymes which work together to replicate the DNA) when the end of the DNA molecule has been reached and replication is finished. (09 Oct 1997) |