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3-ketoacid-CoA transferase <enzyme> An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues.
Synonym: 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase.
(05 Mar 2000)
3-ketoacyl-CoA thiolase <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation.
See: acetyl-CoA acetyltransferase.
Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase.
(05 Mar 2000)
3-methylcrotonyl-CoA (CH3)2C==CHCOSCoA;an intermediate in the degradation of l-leucine; accumulates in a deficiency of 3-methylcrotonyl-CoA carboxylase.
3-methylcrotonyl-CoA carboxylase, an enzyme in the pathway of l-leucine degradation that catalyses the reaction of 3-methylcrotonyl-CoA with CO2, ATP, and water to form ADP, orthophosphate, and 3-methylglutaconyl-CoA; a deficiency of this enzyme causes episodes of severe metabolic acidosis.
(05 Mar 2000)
3-methylglutaconyl-CoA hydratase <enzyme> An enzyme that catalyses the reaction of trans-3-methylglutaconyl-CoA and water to form 3-hydroxy-3-methylglutaconyl-CoA; this enzyme participates in the pathway for l-leucine degradation; a deficiency of this enzyme will result in 3-methylglutaconic aciduria.
(05 Mar 2000)
3-oxoacid-CoA transferase <enzyme> An enzyme catalyzing the reversible conversion of acetoacetyl-CoA and succinate into succinyl-CoA and acetoacetate; malonyl-CoA can substitute for succinyl-CoA and a few other 3-oxo acids for the acetoacetate; an important step in order for the ketone bodies to serve as a fuel for extrahepatic tissues.
Synonym: 3-ketoacid-CoA transferase, acetoacetyl-succinic thiophorase.
(05 Mar 2000)
3-oxobutyryl-CoA reductase <enzyme> Nadh-dependent, (s)-specific enzyme from clostridium tyrobutyricum; n-terminal amino acid sequence given in first source
Registry number: EC 1.1.1.-
(26 Jun 1999)
4-halobenzoate-CoA ligase <enzyme> Involved in conversion of 4-chlorobenzoate to 4-hydroxybenzoate by pseudomonas sp. Cbs3; 115 kD; acts on 4-chloro-, 4-bromo-, 4-iodobenzoate most effectively; 16 n-terminal amino acid sequence determined, with 3 questions, in first source
Registry number: EC 6.2.1.-
Synonym: 4-chlorobenzoate-CoA ligase, 4-cba-CoA ligase, 4-chlorobenzoate-coenzyme a ligase
(26 Jun 1999)
4-hydroxybenzoyl-CoA hydrolase <enzyme> Final enzyme in the degradation of 4-chlorobenzoic acid by pseudomonas; liberates 4-hydroxybenzoic acid; amino acid sequence has been determined
Registry number: EC 3.1.2.-
Synonym: 4-hydroxybenzoyl-coenzyme a thioesterase, 4-hba-CoA thioesterase
(26 Jun 1999)
4-hydroxybutyrate CoA-transferase <enzyme> Forms 4-hydroxybutyryl-CoA from 4-hydroxybutyrate and acetyl-CoA
Registry number: EC 2.8.3.-
Synonym: 4-hydroxybutyrate coenzyme a transferase
(26 Jun 1999)
4-hydroxybutyryl-CoA dehydratase <enzyme> Forms vinylacetyl-CoA from 4-hydroxybutyryl-CoA
Registry number: EC 4.2.1.-
Synonym: gamma-hydroxybutyryl-CoA dehydratase
(26 Jun 1999)
5-hydroxyvalerate CoA-transferase <enzyme> Catalyses the formation of 5-hydroxyvaleryl-CoA from 5-hydroxyvalerate and acetyl-CoA; also acts on propionate and 5-hydroxy-2-pentenoate
Registry number: EC 2.8.3.-
(26 Jun 1999)
5-hydroxyvaleryl-CoA dehydratase <enzyme> Contains fad; bifunctional enzyme which catalyses reversible dehydration of 5-hydroxyvaleryl-CoA to 4-pentenoyl-CoA
Registry number: EC 4.2.1.-
Synonym: 5hvc-dehydratase, 5-hydroxyvaleryl-CoA dehydratase-dehydrogenase
(26 Jun 1999)
lignoceroyl-CoA ligase <enzyme> Requires ATP and mg
Registry number: EC 6.2.1.-
Synonym: lignoceroyl-coenzyme a ligase
(26 Jun 1999)
lignoceroyl-CoA oxidase <enzyme> Catalyses the beta-oxidation of lignoceroyl-CoA
Registry number: EC 1.3.3.-
(26 Jun 1999)
long-chain 3-hydroxyacyl CoA dehydrogenase <enzyme> Deficiency may cause some cases of hypoglycaemic 3-hydroxydicarboxylic aciduria
Registry number: EC 1.1.1.211
Synonym: l-chad
(26 Jun 1999)
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coarctation of the aorta A severe narrowing of the aorta, causing a decrease in blood flow to the lower part of the body. This narrowing is a congenital defect and can be corrected with surgery.
Ãâó: www.clevelandclinic.org/heartcenter/pub/glossary/c...
coagulant A chemical which causes dispersed colloidal particles to become destabilised, thereby aiding in their removal during municipal water treatment. aluminium and iron salts are commonly used for this purpose.
Ãâó: www.deh.gov.au/settlements/industry/finance/glossa...
coagulation process of changing into or being changed into a clot
Ãâó: www.southalabama.edu/alliedhealth/cls/Ravine/gloss...
coagulate to cause to clot or become clotted; to convert a fluid or substance in solution into a solid or a gel. coagulative (adj.) as in coagulative necrosis - a type of necrosis in which affected cells or tissue are converted into a dry, dull, homogeneous eosinophilic mass without nuclei as a result of the coagulation of protein.
Ãâó: www.uwo.ca/pathol/glossary.html
coagulopathy A defect in the bloods ability to clot.
Ãâó: www.lsdn.com/glance_glossary.shtml
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CoA a covering (plate or mat) that protects the surface of a table (i.e., from the condensation on a cold glass or bottle)
CoA someone who coasts
CoA a resident of a coastal area
CoA a brake on a bicycle that engages with reverse pressure on the pedals
CoA a child's four-wheeled toy cart sometimes used for coasting
CoA a military service responsible for the safety of maritime traffic in coastal waters
CoA a member of a coastguard
CoA land in a coastal area
CoA the outline of a coast
CoA in the direction of the coast
CoA along or following a coast
CoA by way of, or along the coast
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