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d-aminolevulinic acid synthase <enzyme> An enzyme that catalyses the reaction of succinyl-CoA with glycine to form d-aminolevulinic acid, coenzyme A, and CO2. The committed step in porphyrin biosynthesis.
Acronym: ALA
(05 Mar 2000)
daunorubicin-doxorubicin polyketide synthase <chemical> Required for doxorubicin biosynthesis; involved in the selection of propionyl-CoA as the starter unit to the formation of a decaketide and its cyclization to an aklanonic acid to the formation of doxorubicin; genbank l35560
Synonym: dnr-dxr pks, doxorubicin polyketide synthase, dxr pks, dps gene product
(26 Jun 1999)
dehydrosqualene synthase <enzyme> Involved in the synthesis of yellow carotenoid 4,4'-diaponeurosporene in staphylococcus aureus; 254 amino acids, mw 30 kD; amino acid sequence given in first source (orf1); genbank x73889
Registry number: EC 1.3.-
Synonym: crtm protein, crtm gene product
(26 Jun 1999)
delta(1)-tetrahydrocannabinolic acid synthase <enzyme> Catalyses the oxidocyclization of cannabigerolic acid without requiring molecular oxygen, coenzymes, or cofactors; n-terminal amino acid sequence given in first source
Registry number: EC 5.3.-
Synonym: delta(1)-thca synthase
(26 Jun 1999)
delta-cadinene synthase <enzyme> Catalyses conversion of farnesylpyrophosphate to (+)-delta-cadinene; isolated from cotton.
Registry number: EC 5.-
(26 Jun 1999)
deoxyhypusine synthase <enzyme> Catalyses the transfer of the 4-aminobutyl moiety from spermidine to the epsilon amino group of a specific lysine residue
Registry number: EC 1.5.1.-
Synonym: spermidine dehydrogenase (nad, l-deoxyhypusyl-forming)
(26 Jun 1999)
deoxyxylulose-5-phosphate synthase <enzyme> Catalyses thiamin diphosphate-dependent acyloin condensation between pyruvate and glyceraldehyde
Registry number: EC 2.2.1.-
Synonym: dxp synthase
(26 Jun 1999)
synthase Trivial name used in Enzyme Commission Report for a lyase reaction going in the reverse direction (NTP-independent). For individual synthase's, see the specific names.
See: synthetase.
(05 Mar 2000)
diglucosyldiacylglycerol synthase <enzyme> Catalyses formation of major, lamellar-forming diglucosyldiacylglycerol from major, nonlamellar-prone monoglucosyldiacylglycerol; isolated from acholeplasma laidlawii
Registry number: EC 2.4.1.-
Synonym: diglucosyl diacylglycerol synthase, dglcdag synthase
(26 Jun 1999)
dihydropteroate synthase <enzyme> An enzyme that catalyses the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
Chemical name: 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase
Registry number: EC 2.5.1.15
(12 Dec 1998)
divinyl ether synthase <enzyme> Catalyses conversion of hydroperoxides to divinyl ethers; isolated from garlic bulbs allium sativum; preferentially acts sterospecifically on the (s) enantomer of 13-hpod ((9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid
Registry number: EC 1.-
(26 Jun 1999)
D-myo-inositol-3-phosphate synthase <enzyme> Catalyses conversion of d-glucose-6-phosphate to d-myo-inositol-3-phosphate
Registry number: EC 5.5.1.-
Synonym: inositol-3-phosphate synthase, ins3p synthase
(26 Jun 1999)
dTDP-D-glucose synthase <enzyme> Catalyses the formation of dtdp-d-glucose by using glucose-1-phosphate and dttp as substrates; rfba is a dual function enzyme; rfba is also a phosphomannose isomerase-guanosine diphosphomannose pyrophosphorylase; see record of pmi-GMP
Registry number: EC 2.7.7.-
Synonym: rfba protein, deltatdp-glucose synthase, tyla1 gene product, rfba gene product
(26 Jun 1999)
dTDP-L-rhamnose synthase <enzyme> Catalyses the formation of dtdp-l-rhamnose by using rhamnose-1-phosphate and dttp as substrates; rfbd is a putative oxidoreductase
Registry number: EC 2.7.7.-
Synonym: rfbd protein, rfbd gene product
(26 Jun 1999)
indole-3-glycerol-phosphate synthase <enzyme> An enzyme in the tryptophan biosynthetic pathway.
Chemical name: 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)
Registry number: EC 4.1.1.48
(12 Dec 1998)
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