| aminophylline | <drug> An inhibitor of cAMP phosphodiesterase. (18 Nov 1997) |
|---|---|
| aminopromazine | 10-[2,3-Bis(dimethylamino)propyl]phenothiazine;an intestinal antispasmodic. (05 Mar 2000) |
| aminopropionic acid | <amino acid> Alanine is a nonessential amino acid that can be manufactured by the body from other sources as needed. Alanine is one of the simplest of the amino acids and is involved in the energy-producing breakdown of glucose. In conditions of sudden anaerobic energy need, when muscle proteins are broken down for energy, alanine acts as a carrier molecule to take the nitrogen-containing amino group to the liver to be changed to the less toxic urea, thus preventing buildup of toxic products in the muscle cells when extra energy is needed. Because the body easily constructs alanine from other sources, no deficiency state is known. Alanine is found in a wide variety of foods, but is particularly concentrated in meats. (22 May 1997) |
| aminopropionitrile | <chemical> 3-aminopropanenitrile. Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid. Chemical name: Propanenitrile, 3-amino- (12 Dec 1998) |
| aminopterin | <drug> A folic acid analogue and inhibitor of dihydrofolate reductase. A potent cytotoxic agent used in the treatment of acute leukaemia. (18 Nov 1997) |
| aminopyridines | Pyridines substituted in any position with an amino group. May be hydrogenated, but must retain at least one double bond. (12 Dec 1998) |
| aminopyrine | <chemical> A drug with analgesic, anti-inflammatory, and antipyretic properties but, owing to the risk of agranulocytosis, whose use is discouraged. Pharmacological action: non-steroidal anti-inflammatory agents. Chemical name: 3H-Pyrazol-3-one, 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl- (12 Dec 1998) |
| aminopyrine n-demethylase | <enzyme> Registry number: EC 1.5.3.- (12 Dec 1998) |
| aminoquinolines | Quinolines substituted in any position by one or more amino groups. (12 Dec 1998) |
| aminorex | <chemical> 2-amino-5-phenyl-2-oxazoline. An amphetamine-like anorectic agent. It may cause pulmonary hypertension. Pharmacological action: appetite depressants. Chemical name: 2-Oxazolamine, 4,5-dihydro-5-phenyl- (12 Dec 1998) |
| aminosalicylic acids | Amino-2-hydroxybenzoic acids. A group of hydroxybenzoic acids that include substitution by amino groups at the 3-, 4-, 5-, or 6-position. The 4-amino derivative, p-aminosalicylic acid, is an antitubercular agent. (12 Dec 1998) |
| aminotransferase | <enzyme> A family of enzymes that catalyse the transfer of an amino group from an alpha-amino acid to an alpha-keto acid, as in the transfer from glutamic acid to oxaloacetic acid, to form aspartic acid and alpha ketoglutarate. One reactant is often glutamic acid and the reactions employ pyridoxal phosphate as co-enzyme. (04 May 1997) |
| aminotransferases | Enzymes transferring amino groups between an amino acid to (usually) a 2-keto acid; e.g., l-alanine and 2-ketoglutarate. Often, the amino acid is an alpha-amino acid. Synonym: aminopherases, transaminases. (05 Mar 2000) |
| aminotriazole | <chemical> An effective weed killer that also possesses some antithyroid activity. Chemical name: 3-amino-1H-1,2,4-triazole Synonym: amitrole. (14 Aug 2000) |
| aminotripeptidase | <enzyme> An intestinal peptidase that acts on tripeptides, releasing an amino acid and a dipeptide. (14 Aug 2000) |