| acute transverse myelitis | Acute inflammation and softening of the spinal cord; involves the entire thickness of the spinal cord but of limited longitudinal extent; multiple aetiologies. (05 Mar 2000) |
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| acute trypanosomiasis | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| acute tuberculosis | A rapidly fatal disease due to the general dissemination of tubercle bacilli in the blood, resulting in the formation of miliary tubercles in various organs and tissues, and producing symptoms of profound toxaemia. Synonym: acute miliary tuberculosis, disseminated tuberculosis. (05 Mar 2000) |
| acute tubular necrosis | <nephrology> A kidney disorder that results in damage to the renal tubule cells leading to acute renal failure. Acute tubular necrosis can result from any condition which deprives the kidney of oxygen (ischaemia). Acute tubular necrosis may occur as a complication of shock, trauma or sepsis. Conditions such as diabetes or liver disease can predispose people to the development of acute tubular necrosis. Certain medications (for example aminoglycosides, amphotericin B, cyclosporine) are known to cause acute tubular necrosis as a toxic side effect. Radiopaque contrast dyes, used in some radiologic procedures, may also result in acute tubular necrosis as a rare complication from contrast dye use. Acronym: ATN (13 Nov 1997) |
| acute urethral syndrome | <syndrome> This describes a clinical syndrome of dysuria (pain on urination) with sterile or low bacterial colony count culture results. Many of these patients have early or low-grade E. Coli, Staphylococcal saprophyticus or Chlamydia trachomatis infections. All are treated with antibiotics. (27 Sep 1997) |
| acute urticaria | Urticaria accompanied by slight constitutional symptoms. Synonym: acute urticaria, urticaria acuta, urticaria febrilis. (05 Mar 2000) |
| acute vascular occlusion | <cardiology, surgery> A serious condition that results from the sudden blockage of an artery, usually with a blood clot. (27 Sep 1997) |
| acute vascular purpura | <dermatology> This relatively rare disorder is characterised by skin purpura, joint pains, abdominal pain and renal disease (glomerulonephritis). Although Henoch-Schonlein purpura or anaphylactoid purpura, is thought to be a immune complex mediated disease, its exact cause is unknown. Its typical benign coarse can, however, include renal failure. (27 Sep 1997) |
| acute viral conjunctivitis | An epidemic inflammation of the conjunctiva marked by follicles, especially in the lower fornix; may be caused by adenoviruses, herpesvirus, and Newcastle disease virus. (05 Mar 2000) |
| acute yellow atrophy of the liver | A lesion in which there is extensive and rapid death of parenchymal cells of the liver, sometimes with fatty degeneration of the size of the organ; the necrosis may result from fulminant viral infection or chemical poisoning; associated with jaundice. Synonym: acute parenchymatous hepatitis, Rokitansky's disease. (05 Mar 2000) |
| acute-phase protein | <haematology> These plasma proteins (in addition to fibrinogen) increase 25% or more in response to inflammation and injury are under direct control of interleukin-6 (IL-6) (hepatocyte-stimulating factor). Other proteins which increase are ceruloplasmin, C3 and C4 which increase 50% or more; alpha-1 acid glycoprotein, alpha-1 antitrypsin, haptoglobin and fibrinogen (the major determinant of viscosity 1 ) which increase two- to fourfold; C-reactive protein (CRP) and serum amyloid A which increase several hundred-fold. Despite long-held clinical opinion to the contrary, available data indicate that neither ESR nor measurement of specific acute-phase reactants are useful in excluding underlying infection or inflammation regardless of the pretest probability. These proteins are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. They can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumour markers. See also: amyloid, c-reactive protein, erythrocyte sedimentation rate, viscosity. (25 Jun 1999) |
| acute-phase reaction | <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms. It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors. (12 Jul 2000) |
| acuteness | 1. The quality of being acute or pointed; sharpness; as, the acuteness of an angle. 2. The faculty of nice discernment or perception; acumen; keenness; sharpness; sensitiveness; applied to the senses, or the understanding. By acuteness of feeling, we perceive small objects or slight impressions: by acuteness of intellect, we discern nice distinctions. "Perhaps, also, he felt his professional acuteness interested in bringing it to a successful close." (Sir W. Scott) 3. Shrillness; high pitch; said of sounds. 4. <medicine> Violence of a disease, which brings it speedily to a crisis. Synonym: Penetration, sagacity, keenness, ingenuity, shrewdness, subtlety, sharp-wittedness. Source: Websters Dictionary (01 Mar 1998) |
| acutifoliate | <botany> Having sharp-pointed leaves. Origin: L. Acutus sharp + folium leaf. Source: Websters Dictionary (01 Mar 1998) |
| acutilobate | <botany> Having acute lobes, as some leaves. Origin: L. Acutus sharp + E. Lobe. Source: Websters Dictionary (01 Mar 1998) |
| acute |
Symptoms or signs that begin and worsen quickly; not chronic.
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| acu- |
(acu-) [L. acus needle] a combining form denoting relationship to a needle.
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