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methyl xanthine <chemical, drug> Naturally occurring purine alkaloids such as theobromine, theophylline and caffeine (trimethyl xanthine). They inhibit cAMP phosphodiesterase and thus cause an increase in the intracellular cAMP concentration.
(18 Nov 1997)
xanthine <biochemistry> A purine, the starting point for purine degradation. Its methylated derivatives (theophylline, theobromine, caffeine) are potent cAMP phosphodiesterase inhibitors.
(18 Nov 1997)
xanthine alkaloids Alkaloids, which contain xanthine as their nitrogenous base.
(12 Dec 1998)
xanthine bronchodilator <pharmacology> A group of medications that work by a common mechanism to effect bronchodilation (open up air passages) in the lungs. Used in the treatment of asthma and related conditions.
Examples include: theophylline, aminophylline and dyphylline.
(27 Sep 1997)
xanthine dehydrogenase <enzyme> An enzyme that catalyses the oxidation of xanthine in the presence of NAD+ to form urate and NADH. It acts also on a variety of other purines and aldehydes.
Chemical name: Xanthine:NAD+ oxidoreductase
Registry number: EC 1.1.1.204
(12 Dec 1998)
xanthine nucleotide The monophosphoric ester of xanthosine. An intermediate in GMP biosynthesis.
Synonym: xanthidylic acid, xanthine nucleotide, xanthylic acid.
(05 Mar 2000)
xanthine oxidase <enzyme> Dehydrogenases involved in conversion of hypoxanthine to xanthine and xanthine to uric acid, as the final catabolism of purines. Deficient in the human disease xanthinuria.
(18 Nov 1997)
xanthine ribonucleoside 9-beta-d-ribosylxanthine;the deamination product of guanosine (O replacing -NH2).
Synonym: xanthine ribonucleoside.
Abbreviation: Xao
(05 Mar 2000)
hypoxanthine-guanine-xanthine phosphoribosyltransferase <enzyme> From tritrichomonas foetus; in contrast to EC 2.4.2.8, this enzyme also uses xanthine as substrate; mw 24 kD
Registry number: EC 2.4.2.-
Synonym: hgxprtase
(26 Jun 1999)
desulfo xanthine dehydrogenase <enzyme> Naturally occuring inactive form of xanthine dehydrogenase
Registry number: EC 1.1.1.-
(26 Jun 1999)
alum stone <chemical> A subsulphate of alumina and potash; alunite.
Source: Websters Dictionary
(01 Mar 1998)
amazon stone <chemical> A variety of feldspar, having a verdigris-green colour.
Origin: Named from the river Amazon.
Source: Websters Dictionary
(01 Mar 1998)
artificial stone A specially calcined gypsum derivative similar to plaster of Paris, but stronger, because the grains are nonporous.
(05 Mar 2000)
bladder stone A condition where small stones form within the urinary tract.
See: kidney stones.
(27 Sep 1997)
vein stone <cardiology, pathology> A concretion or stone within a cardiovascular vein.
Origin: Gr. Phlebos = vein.
(11 Jun 1998)
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