| vitronectin | <protein> Serum protein (70 kD) also called serum spreading factor from its activity in promoting adhesion and spreading of tissue cells in culture. Contains the cell binding sequence Arg Gly Asp (RGD) first found in fibronectin. (18 Nov 1997) |
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| receptors, vitronectin | Alpha-v beta-3 integrins that bind vitronectin with high affinity and play a role in cell migration. They also bind fibrinogen, von willebrand factor, osteopontin, and thrombospondin. The highly homologous alpha-v beta-5 integrin also binds vitronectin, but mediates simple adhesion. (12 Dec 1998) |
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