| 영문 | toxicity | 한글 | 독성 |
|---|---|---|---|
| 설명 | 생체에 있어 바람직하지 않은 약물 작용을 말한다. 약물을 과량으로 사용하면 중독을 일으키며, 심한 경우에는 죽음에 이르는데 이는 약물의 급성 독성이다. 만성 독성은 소량을 장기간 반복 섭취하였을 때의 독성이다. 간, 콩팥 등 여러 장기와 조직에 대한 독성 외에, 기형유발성, 발암성 등도 약물독성이다. 약물독성의 강약은 급성 독성검사(LD50), 만성 독성검사, 기형유발검사, 발암검사, 번식검사 기타 여러 동물검사에 의해 판정된다. |
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| 영문 | alkaloid | 한글 | 알칼로이드 |
|---|---|---|---|
| 설명 | 식물체 속에 들어 있는 질소를 포함한 염기성 유기 화합물을 통틀어 이르는 말. 독성이 있으며 진통, 진해, 마취 작용을 한다. 니코틴, 모르핀, 카페인 따위가 있다. 질소가 포함되어 있는 염기성이며, 대부분은 비교적 소량으로 사람이나 동물에 현저한 약리작용을 나타내는 유기화합물이다. 보통은 식물에서 유래된 식물알칼로이드를 말한다. 피리딘-퀴놀린-이소퀴놀린-피롤리딘-피페리딘-인돌-트로판-퓨린 등 고리구조를 갖는 것이 많고, 대부분은 무색결정성 고체로 식물의 액포 내에서 산과염을 형성하고 있다. 하나의 식물이 수종의 알칼로이드를 포함하는 경우는 보통이며, 미숙한 양귀비 씨의 유액에서 나온 아편 등에는 약 20종류가 포함되어 있다. |
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| ECG | Electro-Cardio-Graphy(-Gram); 심전도 = EKG 1. Conducting System Structu... |
|---|---|
| PA | panic attack; pantothenic acid; paralysis agitans; paranoia; passive aggressive; pathology; patient'... |
| EUROTOX | European Committee on Chronic Toxicity Hazards |
| I&T | intolerance and toxicity |
| TCLP | Toxicity Characteristic Leachate Procedure [EPA battery test] |
| CTC | Common Toxicity Criteria |
|---|---|
| DLT | Dose limiting toxicity |
| RRT | Regimen related toxicity |
| TCLP | Toxicity Characteristic Leaching Procedure |
| TIE | Toxicity Identification Evaluation |
rauwolfine (라월핀
| vinca alkaloid | <drug, oncology> Anti-cancer drugs originally derived from the common periwinkle Catharantus roseus. Drugs of this type include vincristine, vinblastine. (14 Oct 1997) |
|---|---|
| vinca alkaloids | <chemical> A class of alkaloids from the genus of apocyanaceous woody herbs including periwinkles. They are some of the most useful antineoplastic agent. Pharmacological action: antineoplastic agent, phytogenic, vasodilator agents. (12 Dec 1998) |
| Vinca rosea | A species of myrtle (family Myrtaceae) used in various parts of the world as a home remedy; two active dimeric alkaloids obtained from this plant are vinblastine and vincristine. Synonym: periwinkle. (05 Mar 2000) |
| alkaloid | <chemistry, pharmacology> One of a large group of nitrogenous substances found in naturally in plants. They are usually very bitter and although the plant may be poisonous, many have extracts that are pharmacologically active. Examples are atropine, caffeine, coniine, morphine, nicotine, quinine, strychnine. The term is also applied to synthetic substances which have structures similar to plant alkaloids, such as procaine. (29 Sep 1997) |
| belladonna alkaloid | Atropine and related alkaloids which are anticholinergic. (27 Sep 1997) |
| ergot alkaloid-associated heart disease | Heart disease caused by endomyocardial fibrosis which extends into valve structures, producing stenosis and/or regurgitation, associated with ergot alkaloid use. (05 Mar 2000) |
| fixed alkaloid | A nonvolatile alkaloid. (05 Mar 2000) |
| acute toxicity | <pharmacology> Illness resulting from a single dose or exposure to a toxic substance. Compare: chronic toxicity. (06 May 1997) |
| chronic toxicity | <pharmacology> Illness caused by repeated or long-term exposure to low doses of a toxic substance. Compare: acute toxicity. (09 Oct 1997) |
| digitalis toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| digoxin toxicity | A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor. Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels. (27 Sep 1997) |
| drug toxicity | The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. (27 Sep 1997) |
| oxygen toxicity | A body disturbance resulting from breathing high partial pressures of oxygen; characterised by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation. Synonym: oxygen poisoning. (05 Mar 2000) |
| toxicity | The quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. (18 Nov 1997) |
| toxicity test | <investigation> Controlled laboratory test to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations. An acute toxicity test establishes the concentration required to kill a predetermined proportion of test organisms within a relatively short period of time, typically 4 days or less. A chronic toxicity test reveals the effects of a sublethal concentration applied throughout all or part of the life cycle. (12 Jan 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|