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concordance Agreement in the types of data that occur in natural pairs. For example, in a trait like schizophrenia, a pair of identical twins is concordant if both are affected or both are unaffected; it is discordant if one of them only is affected. Likewise, the pairs might be non-identical twins, or sibs, or husband and wife, etc.
Origin: L. Concordia, agreeing, harmony
(05 Mar 2000)
concordance rate The proportion of a random sample of pairs that are concordant for a trait of interest. A high rate of concordance may be generated in several ways, many of which may result from irrelevant bias; but broadly it is taken as evidence of causal connection (e.g., in the case of identical twins, a genetic component or in spouses of assortative mating).
(05 Mar 2000)
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