| uridine monophosphate kinase | <enzyme> Catalyses the phosphorylation of ump to udp; an aspect of EC 2.7.4.4 Registry number: EC 2.7.4.- Synonym: ump kinase, uridine-5-monophosphate kinase, uridylate kinase (26 Jun 1999) |
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| cyclic uridine 3',5'-monophosphate | A cyclic nucleotide involved in metabolic regulation; inhibits the growth of some tumours. (05 Mar 2000) |
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| uridine 5'-monophosphate | Uridine esterified by phosphoric acid on one or more sugar hydroxyl groups; UMP is typically uridine 5'-monophosphate; 2' and 3' derivatives also occur; precursor for the biosynthesis of other pyrimidine nucleotides. Synonym: UMP synthase, uridine 5'-monophosphate. Uridylic acid synthase, a bifunctional enzyme that contains the activities of both orotate phosphoribosyltransferase and orotidine-5'-monophosphate decarboxylase; catalyses a key step in pyrimidine biosynthesis; a deficiency of this enzyme leads to orotic aciduria. (05 Mar 2000) |
| uridine 5'-monophosphate synthase | <chemical> Consists of orotate phosphoribosyltransferase EC 2.4.2.10 and orotidylate decarboxylase EC 4.1.1.23 Chemical name: synthase, uridylate Synonym: ump synthase, uridine 5'-phosphate synthase, uridylate synthase (26 Jun 1999) |
| uridine monophosphate | <chemical> 5'-uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Chemical name: 5'-Uridylic acid (12 Dec 1998) |
| MAP kinase kinase kinase | <enzyme> From pc12 cells; reactivates map kinase kinase inactivated by protein phosphatase 2a by phosphorylation of serine residues; tak1 (tgf-beta-activated kinase 1) is a member of the mapkkk family; genbank ab006787 (mouse) Registry number: EC 2.7.10.- Synonym: mapkkk, tak1 mapkkk, ask1 (kinase), apoptosis signal-regulating kinase 1 (26 Jun 1999) |
| uridine diphosphate kinase | <enzyme> Aspect of EC 2.7.4.6 Registry number: EC 2.7.4.- Synonym: udp kinase (26 Jun 1999) |
| uridine kinase | <enzyme> An enzyme that catalyses the phosphorylation of uridine and cytidine to uridine 5'-phosphate and cytidine 5'-phosphate, respectively. ATP, dutp, dGTP, and datp are effective phosphate donors. Chemical name: ATP:uridine 5'-phosphotransferase Registry number: EC 2.7.1.48 (12 Dec 1998) |
| AMP-activated protein kinase kinase | <enzyme> An endogenous kinase kinase; reactivates the inactive form of AMP-activated protein kinase (AMP-pk); phosphorylates the 63-kD subunit of AMP-pk Registry number: EC 2.7.1.- Synonym: AMP-pk reactivator, hmg CoA reductase kinase kinase (26 Jun 1999) |
| calmodulin-dependent protein kinase IV kinase | <enzyme> Phosphorylates and activates cam-kinase iv; from brain Registry number: EC 2.7.10.- Synonym: cam-kinase iv kinase (26 Jun 1999) |
| MAPKAP kinase-2 reactivating kinase | <enzyme> A mapk-like enzyme; homologous to p42(mapk) and p44(mapk); activated by phosphorylation of serine/threonine and tyrosine residues Registry number: EC 2.7.1.- Synonym: mapkap kinase-2 rk (26 Jun 1999) |
| ribosomal protein S6 kinase kinase | <enzyme> Isolated from unfertilised xenopus eggs; a 41 kD enzyme that is associated, in vivo, with phosphorylation on threonine and tyrosine residues and, in vitro, with phosphorylation on serine as well Registry number: EC 2.7.1.- Synonym: rsk kinase (26 Jun 1999) |
| protein kinase B kinase | <enzyme> Phosphorylates and activates protein kinase b on threonine-308; requires phosphatidylinositol-3,4,5-trisphosphate Registry number: EC 2.7.10.- Synonym: upstream kinase, pkb kinase (26 Jun 1999) |
| leukocyte tyrosine kinase receptor tyrosine kinase | <enzyme> May be receptor for pre-b lymphocyte growth or differentiation factor; aa sequence given in first source Registry number: EC 2.7.1.- Synonym: ltk receptor tyrosine kinase, ltk receptor tk, ltk protein, leukocyte tyrosine kinase (ltk) (26 Jun 1999) |
| adenosine 3',5'-cyclic monophosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| adenosine monophosphate | <chemical> Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Chemical name: 5'-Adenylic acid (12 Dec 1998) |