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uricase <enzyme> An enzyme that catalyses the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin.
Chemical name: Urate:oxygen oxidoreductase
Registry number: EC 1.7.3.3
(12 Dec 1998)
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polyethylene glycol-uricase <chemical> Uricase covalently attached to polyethylene glycol, modifying 71% of amino groups and retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid
Synonym: peg-uricase, methoxypolyethylene glycol uricase
(26 Jun 1999)
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