| uracil | <biochemistry> The pyrimidine base from which uridine is derived. (18 Nov 1997) |
|---|---|
| uracil-6-carboxylic acid | Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate). (18 Nov 1997) |
| uracil dehydrogenase | An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine. Synonym: uracil oxidase. (05 Mar 2000) |
| uracil-DNA glycosidase | <enzyme> Catalyses hydrolysis of n-glycosidic bond of damaged nucleotide residues to give free uracil and partly depyrimidinated DNA of unaltered chain length; does not cleave phosphodiester bonds; a DNA repair enzyme Registry number: EC 3.2.2.- Synonym: ura-DNA glycosidase, uracil-DNA glycosylase, uracil n-glycosidase, ura-DNA glycosylase, uracil n-glycosylase (26 Jun 1999) |
| uracil mustard | <chemical> Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage. Pharmacological action: antineoplastic agent, alkylating. Chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)- (12 Dec 1998) |
| uracil oxidase | An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine. Synonym: uracil oxidase. (05 Mar 2000) |
| uracil permease | <chemical> Mediates uptake of uracil in eucaryotic organisms; does not transport other natural pyrimidines such as cytosine, thymine or uridine Chemical name: permease, uracil Synonym: n 137 (26 Jun 1999) |
| uracil phosphoribosyltransferase | See: phosphoribosyltransferase. (05 Mar 2000) |