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uracil oxidase An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine.
Synonym: uracil oxidase.
(05 Mar 2000)
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uracil <biochemistry> The pyrimidine base from which uridine is derived.
(18 Nov 1997)
uracil-6-carboxylic acid Intermediate in the de novo synthesis of pyrimidines. Linked glycosidically to ribose 5' phosphate, orotate forms the pyrimidine nucleotide orotidylate, that on decarboxylation at position 5 of the pyrimidine ring yields the major nucleotide uridylate (uridine 5' phosphate).
(18 Nov 1997)
uracil dehydrogenase An oxidoreductase catalyzing oxidation of uracil to barbituric acid; also oxidises thymine.
Synonym: uracil oxidase.
(05 Mar 2000)
uracil-DNA glycosidase <enzyme> Catalyses hydrolysis of n-glycosidic bond of damaged nucleotide residues to give free uracil and partly depyrimidinated DNA of unaltered chain length; does not cleave phosphodiester bonds; a DNA repair enzyme
Registry number: EC 3.2.2.-
Synonym: ura-DNA glycosidase, uracil-DNA glycosylase, uracil n-glycosidase, ura-DNA glycosylase, uracil n-glycosylase
(26 Jun 1999)
uracil mustard <chemical> Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Pharmacological action: antineoplastic agent, alkylating.
Chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)-
(12 Dec 1998)
uracil permease <chemical> Mediates uptake of uracil in eucaryotic organisms; does not transport other natural pyrimidines such as cytosine, thymine or uridine
Chemical name: permease, uracil
Synonym: n 137
(26 Jun 1999)
uracil phosphoribosyltransferase See: phosphoribosyltransferase.
(05 Mar 2000)
acetaldehyde oxidase <enzyme> Acetaldehyde is converted to acetate
Registry number: EC 1.2.-
(26 Jun 1999)
acyl-CoA oxidase <enzyme> Catalyses stoichiometric conversion of palmitoyl-CoA and o2 into 2-hexadecenoyl-CoA and h2o2; oxidises acyl-CoA's with carbon chain lengths of 4 to 20; most active toward lauroyl-CoA, but not acetyl- or succinyl-CoA
Registry number: EC 1.3.3.6
Synonym: fatty acyl CoA oxidase, fatty acyl-coenzyme a oxidase, fatty acid acyl-CoA oxidase, acox, pox1 gene product
(26 Jun 1999)
adrenaline oxidase amine oxidase (flavin-containing)
aldehyde oxidase <enzyme> Broad substrate specificity
Registry number: EC 1.2.3.1
Synonym: n1-methylnicotinamide oxidase I, n-nitrosoreductase
(26 Jun 1999)
alternative oxidase <enzyme> The terminal oxidase in alternative pathway respiration, as seen in plants like sauromatum guttatum (voodoo lily); amino acid sequence for tobacco alternative oxidase (aox1) in first source
Registry number: EC 1.-
Synonym: aox1 gene product, aox2 gene product, aox3 gene product
(26 Jun 1999)
alternative oxidase pathway Pathway of mitochondrial electron transport in higher plants, particularly in fruits and seeds, that does not involve cytochrome oxidase and thus is resistant to cyanide.
(18 Nov 1997)
amine oxidase <enzyme> A group of enzymes including those oxidizing primary monoamines, diamines, and histamine.
They are copper proteins, and, as their action depends on a carbonyl group, they are sensitive to inhibition by saemicarbazide.
Chemical name: Amine:oxygen oxidoreductase (deaminating)(copper-containing)
Registry number: EC 1.4.3.6
(12 Dec 1998)
amine oxidase (copper-containing) An oxidoreductase containing copper, and perhaps pyridoxal phosphate, and carrying out the same reaction as amine oxidase (flavin-containing).
Synonym: amine oxidase (pyridoxal-containing), diamine oxidase, diamino oxyhydrase, histaminase.
(05 Mar 2000)
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