| granulation | 1. The act or process of forming or crystallizing into grains; as, the granulation of powder and sugar. 2. The state of being granulated. 3. <medicine> One of the small, red, grainlike prominences which form on a raw surface (that of wounds or ulcers), and are the efficient agents in the process of healing. The act or process of the formation of such prominences. Origin: Cf. F. Granulation. Source: Websters Dictionary (01 Mar 1998) |
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| granulation tissue | Highly vascularised tissue that replaces the initial fibrin clot in a wound. Vascularisation is by ingrowth of capillary endothelium from the surrounding vasculature. The tissue is also rich in fibroblasts (that will eventually produce the fibrous tissue) and leucocytes. (18 Nov 1997) |