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tylosin <chemical> Macrolide antibiotic obtained from cultures of streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
Pharmacological action: antibiotics, macrolide.
Chemical name: Tylosin
(12 Dec 1998)
tylosin reductase <enzyme> From streptomyces fradiae; catalyses the reduction of tylosin to relomycin in the presence of NADPH; mw 270 kD; inhibited by fad or fmn; shows a broad substrate specificity toward all macrolide aldehydes; may have physiological role of macrolide detoxification for the bacterium; structure of tylosin and relomycin given in first source
Registry number: EC 1.1.1.-
(26 Jun 1999)
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