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lymphocyte lymphocyte A type of non-granular antibodies.
(09 Oct 1997)
tumor 1. <oncology> An abnormal mass of tissue that results from excessive cell division that is uncontrolled and progressive, also called a neoplasm. Tumours perform no useful body function. They may be either benign (not cancerous) or malignant.
2. Swelling, one of the cardinal signs of inflammations, morbid enlargement.
Origin: L. Tumere = to swell
(12 May 1997)
tumor marker <investigation, oncology> A substance in the body that usually indicates the presence of cancer.
These markers are usually specific to certain types of cancer and are usually found in the blood or other tissue samples.
Examples are alphafetoprotein (AFP), human chorionic gonadotropin, and lactate dehydrogenase (LDH).
They may be indicators of tumour stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
(18 Jul 2002)
tumor necrosis factor <cytokine> Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin.
Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine.
Synonym: cachectin.
Acronym: TNF
(13 Nov 1997)
adipose infiltration Growth of normal adult fat cells in sites where they are not usually present.
(05 Mar 2000)
calcareous infiltration <biochemistry> The process by which organic tissue becomes hardened by a deposit of calcium salts within its substance.
Origin: L. Facere = to make.
(21 Mar 1998)
gelatinous infiltration A term sometimes used for the relatively rapidly formed, semisolid, gray or gray-white exudate (chiefly necrotic cells and remnants of tissue, and macrophages) resulting from unusually acute, overwhelming, diffuse tuberculous infection in the lung.
Synonym: gelatinous infiltration.
(05 Mar 2000)
paraneural infiltration Infiltration adjacent to or along a nerve.
(05 Mar 2000)
cellular infiltration Migration of cells from their sources of origin, or direct extension of cells as a result of unusual growth and multiplication, thereby resulting in fairly well-defined foci, irregular accumulations, or diffusely distributed individual cells in the connective tissue and interstices of various organs and tissues; used especially with reference to such changes associated with inflammations and certain types of malignant neoplasms.
(05 Mar 2000)
perineural infiltration Infiltration about a nerve.
(05 Mar 2000)
gray infiltration A term sometimes used for the relatively rapidly formed, semisolid, gray or gray-white exudate (chiefly necrotic cells and remnants of tissue, and macrophages) resulting from unusually acute, overwhelming, diffuse tuberculous infection in the lung.
Synonym: gelatinous infiltration.
(05 Mar 2000)
small bowel infiltration <radiology> Whipple disease (proximal small bowel), small bowel lymphoma, amyloidosis, Waldenstrom macrogloblinaemia, sprue, eosinophilic gastroenteritis, abetalipoproteinaemia (increased fat droplets in mucosal cells)
(12 Dec 1998)
infiltration <pathology> The diffusion or accumulation in a tissue or cells of substances not normal to it or in amounts of the normal. Also, the material so accumulated.
(13 Nov 1997)
infiltration anaesthesia Anaesthesia produced by injection of local anaesthetic solution directly into an area that is painful or about to be operated upon.
(05 Mar 2000)
epituberculous infiltration An infiltration superimposed upon a tuberculous lesion.
(05 Mar 2000)
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