| tuberculin-type hypersensitivity | A local or generalised response that begins 24 to 48 hours after exposure to an antigen. See: cell-mediated reaction. Synonym: contact hypersensitivity, delayed hypersensitivity, late reaction, tuberculin-type hypersensitivity. (05 Mar 2000) |
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| purified protein derivative of tuberculin | Purified tuberculin containing the active protein fraction; the tuberculin from which it is prepared differs from tuberculin chiefly in that the bacteria are grown in a synthetic rather than in a broth medium. (05 Mar 2000) |
| tuberculin | <protein> A protein extracted from the tuberculosis bacteriumMycobacterium tuberculosis. It is used in tests to determine if aperson has been exposed to the bacteria and is in danger of coming down with the disease. (09 Oct 1997) |
| tuberculin skin test | See: Mantoux test, Heaf test, tuberculin tine test (18 Nov 1997) |
| tuberculin test | <investigation> A test for previous infection with Mycobacterium tuberculosis. (09 Oct 1997) |
| tuberculin tine test | <investigation> In this test a small amount of tuberculosis antigen in injected into the skin (dermis). The skin is inspected later to see if a positive skin reaction has occurred. The presence of inflammation indicates that your body has been exposed to tuberculosis antigen at some point in your life. A chest X-ray will be taken to look for signs of TB if your tine test is positive. (27 Sep 1997) |
| Koch's original tuberculin | <protein> A protein extracted from the tuberculosis bacteriumMycobacterium tuberculosis. It is used in tests to determine if aperson has been exposed to the bacteria and is in danger of coming down with the disease. (09 Oct 1997) |
| vasculitis, hypersensitivity | Heterogeneous group of disorders characterised by a vasculitic syndrome presumed to be associated with a hypersensitivity reaction following exposure to an antigen such as an infectious agent, a drug, or other foreign or endogenous substance. (12 Dec 1998) |
| respiratory hypersensitivity | A form of hypersensitivity affecting the respiratory tract. It includes asthma and hay fever. (12 Dec 1998) |
| milk hypersensitivity | Allergic reaction to milk (usually cow's milk) or milk products. In infants the hypersensitivity is manifested by colic, vomiting, diarrhoea, rhinitis, wheezing, etc. Milk hypersensitivity should be differentiated from lactose intolerance, an intolerance to milk as a result of congenital deficiency of lactase. (12 Dec 1998) |
| contact hypersensitivity | <pathology> A type of immune-mediated inflammatory skin rash that results from an allergy to a particular substance (for example jewelry dermatitis, poison ivy, neomycin ointment, etc.). (27 Sep 1997) |
| hypersensitivity | <immunology> A state of altered reactivity in which the body reacts with an exaggerated immune response to a foreign substance. Hypersensitivity reactions are classified as immediate or delayed, types I and IV, respectively, in the Gell and Coombs classification of immune responses. (18 Nov 1997) |
| hypersensitivity, delayed | An increased reactivity to specific antigens mediated not by antibodies but by cells. (12 Dec 1998) |
| hypersensitivity, immediate | Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. (12 Dec 1998) |
| hypersensitivity pneumonitis | <radiology> Aka: chronic extrinsic allergic alveolitis, pathology: proliferation of epithelial cells, elaboration of reticulum fibres, findings: interstitial reticulonodular pattern (basilar distribution), volume loss (cicatrization atelectasis) in upper lobes, pleural effusion (rare), lymph node enlargement may occur (12 Dec 1998) |