| tryptophan 5-monooxygenase |
[EC 1.14.16.4] a monooxygenase that activates molecular oxygen to catalyze the hydroxylation of tryptophan to hydroxytryptophan, a precursor of serotonin; it requires the cofactor tetrahydrobiopterin. The enzyme occurs in the central nervous system and is inactivated in malignant hyperphenylalaninemia.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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