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trimethaphan <chemical> A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anaesthesia, and to induce hypotension during surgery.
Pharmacological action: anaesthesia adjuvants, antihypertensive agents, ganglionic blockers, nicotinic antagonists.
Chemical name: Thieno(1',2':1,2)thieno(3,4-d)imidazol-5-ium, decahydro-2-oxo-1,3-bis(phenylmethyl)-
(12 Dec 1998)
trimethaphan camsylate D-1,3-dibenzyldecahydro-2-oxoimidazo[c]thieno[1,2-a]thiolium camphorsulfonate;a ganglionic blocking agent that produces vasodilation of brief duration; used in surgery, particularly neurosurgery, to produce a relatively bloodless operative field (controlled hypotension).
Synonym: trimetaphan camsylate.
(05 Mar 2000)
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