transforming growth factor beta : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 4 페이지: 1

Transforming Growth Factor beta - 새창 A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Synonyms : Milk Growth Factor, TGFbeta, Bone Derived Transforming Growth Factor, Factor, Milk Growth, Growth Factor, Milk
Transforming Growth Factor beta1 - 새창 A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
Synonyms : TGF-beta-1, TGF-beta1 Latency-Associated Protein, TGF-beta1LAP, Transforming Growth Factor beta 1 Latency Associated Peptide, Transforming Growth Factor beta I, Latency-Associated Protein, TGF-beta1, TGF beta 1, TGF beta1 Latency Associated Protein
Transforming Growth Factor beta2 - 새창 A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Synonyms : BSC-1 Cell Growth Inhibitor, Cartilage-Inducing Factor-B, Glioblastoma-Derived T-Cell Suppressor Factor, Polyergin, Suppressor Factor, T-Cell, Glioblastoma-Derived, TGF-beta-2, TGF-beta2 Latency-Associated Protein, TGF-beta2LAP, BSC 1 Cell Growth Inhibitor
Transforming Growth Factor beta3 - 새창 A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Synonyms : TGF-beta-3, TGF-beta3 Latency-Associated Protein, TGF-beta3LAP, TGFB3, Transforming Growth Factor beta 3 Latency Associated Peptide, Latency-Associated Protein, TGF-beta3, TGF beta 3, TGF beta3, TGF beta3 Latency Associated Protein