transducin : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

Transducin - 새창 A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is pivotal in the visual excitation process. Activation of rhodopsin on the outer membrane of rod and cone cells causes GTP to bind to transducin followed by dissociation of the alpha subunit-GTP complex from the beta/gamma subunits of transducin. The alpha subunit-GTP complex activates the cyclic GMP phosphodiesterase which catalyzes the hydrolysis of cyclic GMP to 5'-GMP. This leads to closure of the sodium and calcium channels and therefore hyperpolarization of the rod cells. EC 3.6.1.-.
Synonyms : Transducin G-Protein (Gt), Transducin, alpha Subunit, Transducin, beta Subunit, Transducin, gamma Subunit, G Protein, Inhibitory Gt, G-Protein Gt, Transducin, Gt G-Protein, Inhibitory, Gt, Transducin G Protein, Inhibitory Gt G-Protein, Transducin G-Protein Gt