| transducin | <protein> A GTP-binding protein found in the disc membrane of retinal rods and cones: of the part of the cascade involved in transduction of light to a nervous impulse. A complex of three subunits, alpha (39 kD), beta (36 kD) and gamma (8 kD). Photoexcited rhodopsin interacts with transducin and promotes the exchange of GTP for GDP on the _ subunit. The GTP _ subunit dissociates from the complex and activates a cGMP phospodiesterase by removing an inhibitory subunit. The _ subunit of transducin can be ADP ribosylated by cholera toxin and pertussis toxin. (18 Nov 1997) |
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| transducin GTP phosphohydrolase | <enzyme> Stimulated by bovine rhodopsin mutants (asp63 to asn) and (glu134 to gln) with slightly lowered efficiency Registry number: EC 3.6.1.- Synonym: transducin GTPase (26 Jun 1999) |