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  • transcription factor
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  • transcription factor II
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    ÀÏÂ÷ Àü»çü(ìéó­ï®ÞÐô÷)
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GAWTS genomic amplification with transcript sequencing
RAWTS ribonucleic acid amplification with transcript sequencing
XIST X-inactivation specific transcript
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CART Cocaine and amphetamine regulated transcript
LAT Latency-associated transcript
RT-PCR Reverse transcript polymerase chain reaction
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 12 ÆäÀÌÁö: 1
transcriptase <enzyme> RNA directed DNA polymerase.
Enzyme first discovered in retroviruses, that can construct double stranded DNA molecules from the single stranded RNA templates of their genomes. Reverse transcription now appears also to be involved in movement of certain mobile genetic elements, such as the Ty plasmid in yeast, in the replication of other viruses such as Hepatitis B and possibly in the generation of mammalian pseudogenes.
(18 Nov 1997)
transcription <molecular biology> Synthesis of RNA by RNA polymerases using a DNA template.
(18 Nov 1997)
transcription factor <molecular biology> Protein required for recognition by RNA polymerases of specific stimulatory sequences in eukaryotic genes.
Several are known that activate transcription by RNA polymerase II when bound to upstream promoters.
Transcription of the 5S RNA gene in Xenopus by RNA polymerase III is dependent on a 40 kD protein TFIIIA that binds to a regulatory site in the centre of the gene and was the first protein found to exhibit the metal binding domains known as zinc fingers.
(17 Mar 1998)
transcription factor ap-1 A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerise in order to bind to the ap-1 recognition site, also known as the tpa-responsive element (tre). Ap-1 controls both basal and inducible transcription of several genes.
(12 Dec 1998)
transcription factor, sp1 Promoter-specific RNA polymerase II transcription factor that binds to the gc box, one of the upstream promoter elements (upe) in mammalian cells. The binding of sp1 is necessary to initiate transcription in the promoters of a variety of cellular and viral genes including c-ha-ras and HIV.
(12 Dec 1998)
transcription factors Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
(12 Dec 1998)
transcription factors, tfii The so-called general transcription factors that bind to RNA polymerase II and that are required to initiate transcription. They include tfiia, tfiib, tfiid, tfiie, tfiif, tfiih, tfii-I, and tfiij. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
(12 Dec 1998)
transcription factors, tfiii Factors that bind to RNA polymerase III and aid in transcription. They include the assembly factors tfiiia and tfiiic and the initiation factor tfiiib. All combine to form a preinitiation complex at the promotor that directs the binding of RNA polymerase III.
(12 Dec 1998)
transcription unit <molecular biology> A region of DNA that is transcribed to produce a single primary RNA transcript, i.e. A newly synthesised RNA molecule that has not been processed.
Transcription units can be mapped by kinetic studies of RNA synthesis and in some instances directly visualised by electron microscopy.
(17 Mar 1998)
transcription, genetic The transfer of genetic information from DNA to messenger RNA by DNA-directed RNA polymerase. It includes reverse transcription and transcription of early and late genes expressed early in an organism's life cycle or during later development.
(12 Dec 1998)
transcriptional control <molecular biology> Control of gene expression by controlling the number of RNA transcripts of a region of DNA. A major regulatory mechanism for differential control of protein synthesis in both pro and eukaryotic cells.
(18 Nov 1997)
transcriptional silencing <molecular biology> Mechanism of transcriptional control where DNA is bundled into heterochromatin in order to make it permanently inaccessible for future transcription.
Effectively, this allows for memory in the determination of cell fate in developing organisms. In Drosophila, homeotic genes are silenced by members of the Polycomb group of genes.
(17 Mar 1998)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
primary transcript <molecular biology> RNA transcript immediately after transcription in the nucleus, before RNA splicing or polyadenylation to form the mature mRNA.
(18 Nov 1997)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • Transcription Factor AP-1 - »õâ A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
    Synonyms : AP-1, AP-1 Enhancer Binding Protein, Activator Protein-1, AP 1 Enhancer Binding Protein, Activator Protein 1, Enhancer-Binding Protein, AP-1, Transcription Factor AP 1
  • Transcription Factor AP-2 - »õâ A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.
    Synonyms : AP-2 alpha Protein, AP-2 beta Protein, AP-2 epsilon Protein, AP-2 gamma Protein, AP-2delta Protein, Activator Protein AP-2, Enhancer-Binding Protein AP-2, TFAP2B Protein, TFAP2alpha Protein, Transcription Factor AP-2 alpha Protein, Transcription Factor AP-2alpha
  • Transcription Factor Brn-3 - »õâ A family of mammalian POU domain factors that are expressed predominately in NEURONS.
    Synonyms : Brn 3 Transcription Factor, Brn-3, Transcription Factor, Transcription Factor Brn 3, Transcription Factor, Brn-3
  • Transcription Factor Brn-3A - »õâ A POU domain factor that activates GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS; alpha internexin; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; and BCL-2 PROTO-ONCOGENE PROTEINS.
    Synonyms : POU Domain, Class 4, Transcription Factor 1, Brn 3A Transcription Factor, Brn-3A, Transcription Factor, Transcription Factor Brn 3A, Transcription Factor, Brn-3A, Transcription Factor, Pou4f1
  • Transcription Factor Brn-3B - »õâ A POU domain factor that represses GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha internexin, and SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.
    Synonyms : POU Domain, Class 4, Transcription Factor 2, Pou4f2 Protein, Brn 3B Transcription Factor, Brn-3B, Transcription Factor, Transcription Factor Brn 3B, Transcription Factor, Brn-3B, Transcription Factor, Pou4f2
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transcriptase a polymerase associated with the process of transcription
Ãâó: wordnet.princeton.edu/perl/webwn
transcription something written, especially copied from one medium to another, as a typewritten version of dictation (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA a sound or television recording (e.g., from a broadcast to a tape recording) arrangement: the act of arranging and adapting a piece of music recording: the act of making a record (especially an audio record); "she watched the recording from a sound-proof booth"
Ãâó: wordnet.princeton.edu/perl/webwn
transcription Transcription is the process through which a DNA sequence is enzymatically copied by an RNA polymerase to produce a complementary RNA. In the case of protein-encoding DNA, transcription is the beginning of the process that ultimately leads to the translation of the genetic code (via the mRNA intermediate) into a functional peptide or protein. ...
Ãâó: en.wikipedia.org/wiki/Transcription_(genetics)
transcriptome All transcribed mRNAs within a cell.
Ãâó: www.genpromag.com/Glossary~LETTER~T.html
transcription The transfer of information from a double-stranded DNA molecule to a single-stranded RNA molecule. It is also called RNA synthesis.
Ãâó: www.modernhumanorigins.com/t.html
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transcript a reproduction of a written record (e.g. of a legal or school record)
transcript a polymerase associated with the process of transcription
transcript the act of making a record (especially an audio record)
transcript a recording (e.g., from broadcast to tape recording)
transcript something written, especially copied from one medium to another, as a typewritten version of dictation
transcript (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA
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