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acute toxicity <pharmacology> Illness resulting from a single dose or exposure to a toxic substance.
Compare: chronic toxicity.
(06 May 1997)
chronic toxicity <pharmacology> Illness caused by repeated or long-term exposure to low doses of a toxic substance.
Compare: acute toxicity.
(09 Oct 1997)
digitalis toxicity A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor.
Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels.
(27 Sep 1997)
digoxin toxicity A result of the over-accumulation of digitalis glycosides in the body. Kidney insufficiency can be a contributing factor.
Symptoms include nausea, vomiting, visual changes, blurred vision, anorexia and palpitations. Treatment is emergent as life-threatening cardiac arrhythmias are possible with higher blood levels.
(27 Sep 1997)
drug toxicity The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug.
(27 Sep 1997)
oxygen toxicity A body disturbance resulting from breathing high partial pressures of oxygen; characterised by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation.
Synonym: oxygen poisoning.
(05 Mar 2000)
toxicity The quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
(18 Nov 1997)
toxicity test <investigation> Controlled laboratory test to determine the toxicity of a chemical to an organism in terms of specific chemical concentrations.
An acute toxicity test establishes the concentration required to kill a predetermined proportion of test organisms within a relatively short period of time, typically 4 days or less. A chronic toxicity test reveals the effects of a sublethal concentration applied throughout all or part of the life cycle.
(12 Jan 1998)
toxicity tests Tests that determine the toxicity of a substance. These include tests of clinical drugs, foods, environmental pollutants, etc.
(12 Dec 1998)
ep toxicity A test defined by the federal Environmental Protection Agency to check a substance for the presence of arsenic, barium, cadmium, chromium, lead, mercury, selenium, or silver. 40 CFR 261.24 defines the concentrations constituting hazardous waste and the test procedure.
(05 Dec 1998)
absorbancy index Absorbance (of light) per unit path length (usually the centimeter) and per unit of mass concentration.
Compare: molar absorption coefficient.
Synonym: absorbancy index, absorptivity, extinction coefficient, specific extinction.
(05 Mar 2000)
alveolar index Relation between the basialveolar (basion to alveolar point) and basinasal (basion to nasion) lengths: (basialveolar length &times; 100)/basinasal length; the result indicates the degree of projection of the maxilla or upper jaw.
Synonym: alveolar index.
(05 Mar 2000)
anaesthetic index Ratio of the number of units of anaesthetic required for anaesthesia to the number of units of anaesthetic required to produce respiratory or cardiovascular failure.
(05 Mar 2000)
antitryptic index An obsolete term for the relative retardation in loss of viscosity of a solution of casein incubated with trypsin, to which a drop of abnormal blood serum (as from a cancerous patient) has been added, compared with that in a similar solution to which normal serum has been added; if the former drips through the tube of the viscosimeter in 100 seconds, and the latter in 104 seconds, the antitryptic index is 4.
(05 Mar 2000)
Arneth index An expression based on adding the percentages of polymorphonuclear neutrophils with 1 or 2 lobes in their nuclei, plus one-half the percentage with 3 lobes; the normal value is 60%.
See: Arneth formula, Arneth count.
(05 Mar 2000)
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