| tosyl | Toluenesulfonyl radical, widely used to block amino groups in the course of organic syntheses of drugs and other biologically active compounds. (05 Mar 2000) |
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| tosylarginine methyl ester | <chemical> N(2)-(p-tolylsulfonyl)-l-arginine, methyl ester. Arginine derivative which is a substrate for many proteolytic enzymes. As a substrate for the esterase from the first component of complement, it inhibits the action of c(l) on c(4). Chemical name: L-Arginine, N2-((4-methylphenyl)sulfonyl)-, methyl ester (12 Dec 1998) |
| tosylarginine methyl ester hydrolase | <enzyme> Protease from sea urchin (arbacia punctulata) eggs; fertilization in the sea urchin is accompanied by the release of this protease from eggs into the surrounding seawater; enzyme uses tame as substrate; used as a measure of trypsin-like activity; tryptase (formerly here) is mast cell tryptase (EC 3.4.21.59) Registry number: EC 3.4.- Synonym: tame hydrolase, tame esterase, esterase a2, n-tosyl-l-arginine methyl ester esterase, tamase, tamase-1 (26 Jun 1999) |
| tosylate | USAN-approved contraction for p-toluenesulfonate. (05 Mar 2000) |
| tosyllysine chloromethyl ketone | <chemical> An inhibitor of serine proteinases. Acts as an alkylating agent and is known to interfere with the translation process. Pharmacological action: alkylating agents, protein synthesis inhibitor, serine proteinase inhibitors. Chemical name: Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl- (12 Dec 1998) |
| tosylphenylalanyl chloromethyl ketone | <chemical> An inhibitor of serine proteinases. Acts as alkylating agent and is known to interfere with the translation process. Pharmacological action: alkylating agents, protein synthesis inhibitor, serine proteinase inhibitors. Chemical name: Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)- (12 Dec 1998) |