| topoisomerase |
Topoisomerases (type I: EC 5.99.1.2, type II: EC 5.99.1.3) are enzymes that act on the topology of DNA. The double-helical configuration that DNA strands naturally reside in makes them difficult to separate, and yet they must be separated by helicase proteins if other enzymes are to transcribe the sequences that encode proteins, or if chromosomes are to be replicated. ...
출처: en.wikipedia.org/wiki/Topoisomerase
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| topoisomer |
a DNA molecule that differs from another only in linking number, the number of times one strand of the helix wraps around the other in a right hand direction.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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