| goodness of fit | Degree of agreement between an empirically observed distribution and a mathematical or theoretical distribution. (05 Mar 2000) |
|---|---|
| goodness of fit test | A statistical test of the hypothesis that data have been randomly sampled or generated from a population that follows a particular theoretical distribution. (05 Mar 2000) |
| induced fit | A change in the conformation of an enzyme due to it binding to asubstrate that makes it catalyticallyactive. A situation where any molecule changes shape as it binds toa ligand so that its bindingsite more closely conforms to the shape of the ligand. (09 Oct 1997) |
| induced fit model | A model to suggest a mode of action of enzymes in which the substrate binds to the active site of the protein, causing a conformational change in the protein. Synonym: Koshland-Nemethy-Filmer model. (05 Mar 2000) |
| uncinate fit | Seizures with elaborate and multiple sensory, motor, and/or psychic components. A common feature is the clouding of consciousness and amnesia for the event. Some clinical manifestations may include more complex behaviours like burst of anger, emotional outbursts, fear or automatisms. The EEG often reveals spike discharges in the temporal lobe during sleep. (27 Sep 1997) |
| fit | Origin: AS. Fit strife, fight; of uncertain origin. 1. A stroke or blow. "Curse on that cross, quoth then the Sarazin, That keeps thy body from the bitter fit." (Spenser) 2. A sudden and violent attack of a disorder; a stroke of disease, as of epilepsy or apoplexy, which produces convulsions or unconsciousness; a convulsion; a paroxysm; hence, a period of exacerbation of a disease; in general, an attack of disease; as, a fit of sickness. "And when the fit was on him, I did mark How he did shake." (Shak) 3. A mood of any kind which masters or possesses one for a time; a temporary, absorbing affection; a paroxysm; as, a fit melancholy, of passion, or of laughter. "All fits of pleasure we balanced by an equal degree of pain." (Swift) "The English, however, were on this subject prone to fits of jealously." (Macaulay) 4. A passing humor; a caprice; a sudden and unusual effort, activity, or motion, followed by relaxation or insction; an impulse and irregular action. "The fits of the season." (Shak) 5. A darting point; a sudden emission. "A tongue of light, a fit of flame." (Coleridge) By fits, By fits and starts, by intervals of action and repose; impulsively and irregularly; intermittently. Source: Websters Dictionary (01 Mar 1998) |
| FIT test | Employment of the phenomenon of cerebral fusion of binaural sounds to substitute for conventional masking in hearing testing. Synonym: FIT test. (05 Mar 2000) |
| bitter tonic | A tonic of bitter taste, such as quinine, gentian, quassia, etc., which acts chiefly by stimulating the appetite and improving digestion. (05 Mar 2000) |
| generalised tonic-clonic epilepsy | tonic-clonic seizure |
| generalised tonic-clonic seizure | <neurology> A type of seizure that results in loss of consciousness, generalised muscle contractions, urinary incontinence, tongue biting and a post-ictal state (confusion and lethargy) following cessation of the seizure. Synonym: grand-mal seizure. See: epilepsy. (03 Jul 1999) |
| secondarily generalised tonic-clonic seizure | A generalised tonic-clonic seizure that begins with a partial seizure and evolves into a generalised tonic-clonic seizure. (05 Mar 2000) |
| tonic | 1. Producing and restoring the normal tone. 2. Characterised by continuous tension. 3. A term formerly used for a class of medicinal preparations believed to have the power of restoring normal tone to tissue. Origin: Gr. Tonikos (18 Nov 1997) |
| tonic-clonic seizure | <neurology> A type of seizure that results in loss of consciousness, generalised muscle contractions, urinary incontinence, tongue biting and a post-ictal state (confusion and lethargy) following cessation of the seizure. Synonym: grand-mal seizure. See: epilepsy. (03 Jul 1999) |
| tonic contraction | Sustained contraction of a muscle, as employed in the maintenance of posture. (05 Mar 2000) |
| tonic control | Nerve impulses that maintain a normal tonus or level of activity in muscle or other effector organs. (05 Mar 2000) |