| 영문 | connective tissue | 한글 | 결합조직 |
|---|---|---|---|
| 설명 | 체내에 널리 분포하며, 장기, 조직사이를 메우고 그것을 기계적으로 지지, 조직이다. 그밖에 혈관, 림프관, 신경을 인도하며 영양, 대사산물의 수송 또는 저류, 나아가서는 손상, 감염에 대한 방어 또는 수복 등에도 작용한다. 결합조직은 세포간질이 풍부하며, 세포간질을 구성하는 기질과 섬유의 성상에 따라 간엽조직, 섬유성 결합조직(성긴섬유성 결합조직, 촘촘한 섬유성 결합조직), 지방조직, 탄성조직, 세망 조직 등으로 분류된다. |
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| 영문 | osseous tissue | 한글 | 뼈조직, 골조직 |
|---|---|---|---|
| 설명 | 골세포와 골세포주위의 딱딱한 칼슘조직으로 둘러싸인 밀집된 결합조직을 뜻한다. 이 골조직에 의해서 뼈가 이루어져 인체의 골격을 형성한다. |
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| 영문 | epithelial tissue | 한글 | 상피조직 |
|---|---|---|---|
| 설명 | 상피는 한 층 또는 여러 층의 세포로 이루어진 판 모양의 구조로 신체의 표면과 관상구조의 내강을 둘러싸고 있다. 상피세포와 상피세포사이의 적은 양으로 존재하여 상피사이의 공간을 채우고 있는 세포간질을 합쳐 상피조직이라 한다. 상피조직에는 원칙적으로 혈관이 분포되어 있지 않다. |
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| 영문 | granulation tissue | 한글 | 육아조직 |
|---|---|---|---|
| 설명 | 모세혈관이 풍부하며 왕성하게 증식을 계속하는 어린 결합조직. 창상 등 조직 결손에 대한 수복, 이물처리의 기질화, 염증이 만성적인 경과에 있거나 종양증식에 동반된 사이물질의 반응성 염증에서 관찰된다. 구성성분은 생긴지 얼마 안되는 어린 육아조직은 섬유모세포의 증식, 새로 생긴 모세혈관과 여러 유주세포 및 다른 중간엽세포(백혈구, 림프구, 형질세포, 조직구, 단핵구, 거대세포)등으로 구성된다. 이것이 시간이 지나 그리되면, 모세혈관과 유주세로, 다른조직성분을 감소시켜 만성화하여 오래된 육아가 되며 결국은 섬유세포와 아교질섬유로 구성된 반흔조직으로 변한다. |
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| 영문 | tissue | 한글 | 조직 |
|---|---|---|---|
| 설명 | 특정 구조와 기능을 갖는 세포 집단. 세포 사이에는 다소간 세포간질이 들어 있다. 세포간질에는 글리코사미노글리칸, 히드록시아파타이트와 같은 기질과 아교질섬유와 같은 섬유가 발견된다. 조직성상은 구성세포와 세포간질의 종류와 양에 의해 결정된다. 조직은 상피조직, 지지조직, 근육조직, 신경조직으로 대별되며, 상피조직은 세포간질을 거의 갖지 않으며, 지지조직은 결합조직이나 뼈조직과 같이 세포간질이 풍부한 것이 많다. |
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| TIMP | tissue inhibitor of metalloproteinases |
|---|---|
| BPTI | basic pancreatic trypsin inhibitor; basic polyvalent trypsin inhibitor; bovine pancreatic trypsin in... |
| PI | first meiotic prophase; isoelectric point; pacing impulse; package insert; pancreatic insufficiency;... |
| ESI | elastase-specific inhibitor; enzyme substrate inhibitor; epidural steroid injection |
| PTI | pancreatic trypsin inhibitor; persistent tolerant infection; Pictorial Test of Intelligence; placent... |
| TIMP | Tissue inhibitor of matrix metalloproteinases |
|---|---|
| MMP | Metalloproteinases |
| rTFPI | Recombinant tissue factor pathway inhibitor |
| TFPI | Tissue Factor Pathway Inhibitor |
| TIMP | Tissue Inhibitor of Metallo Proteases |
acute angle
| tissue inhibitor of metalloproteinases | <chemical> A family of secreted proteins (timp-1, timp-2, and timp-3) that play a crucial role in regulating the activity of the secreted metalloproteinases (collagenases, stromelysins, gelatinases). Of the three characterised, only timp-1 and timp-2 appear to have related primary structures and inhibitory properties. They influence the activation of the prometalloproteinase and act to modulate proteolysis of extracellular matrix, notably during tissue remodeling and inflammatory processes. On certain cell types, they can exhibit growth factor-like activity, and they can inhibit the tumourigenic and metastatic phenotype in cancer cells. (pharmacol ther 1993;59:329-41) Pharmacological action: antineoplastic agent, protease inhibitors. (12 Dec 1998) |
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| metalloproteinases | <enzyme> Peptide hydrolases which use a metal in the catalytic mechanism. This group of enzymes is inactivated by metal chelators. Registry number: EC 3.4.24 (12 Dec 1998) |
|---|---|
| tissue-inhibitor of metalloproteinase-1 | <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a n-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumour invasion in vitro. Pharmacological action: antineoplastic agent, protease inhibitors. (12 Dec 1998) |
| tissue inhibitor-of metalloproteinase-2 | <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a 21 kD nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase a by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of timp-2 has been shown to inhibit invasive and metastatic activity of tumour cells and decrease tumour growth in vivo. Pharmacological action: antineoplastic agent, protease inhibitors. (12 Dec 1998) |
| tissue inhibitor of-metalloproteinase-3 | <chemical> A member of the family of tissue inhibitor of metalloproteinases. It is a 21 kD, nonglycosylated protein. Timp-3 does not show a high degree of structural similarity unlike timp-1 and timp-2 which are structurally similar. However, it does possess a high degree of structural similarity with that of chicken timp-3 (chimp-3). Human timp-3 is of particular concern because of its potential role in cancer, arthritis, and eye diseases. Pharmacological action: antineoplastic agent, protease inhibitors. (12 Dec 1998) |
| a1-trypsin inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
| ACE inhibitor | <pharmacology> A group of antihypertensive medications that work by inhibiting an enzyme (angiotensin-converting enzyme) that is important in the regulation of blood pressure. Studies have also indicated that it may help prevent or slow the progression of kidney disease in patients with diabetes. Examples include: captopril, ramipril, enalapril, losartan potassium, bepridil and lisinopril. (12 Mar 1998) |
| aldose reductase inhibitor | <pharmacology> A class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body. It helps change glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy. Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes. (09 Oct 1997) |
| angiotensin-converting enzyme inhibitor | <pharmacology> A class of drugs used in the treatment of hypertension and heart failure. They exert their haemodynamic effect mainly by inhibiting the renin-angiotensin system and produce a reduction of peripheral arterial resistance. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. (14 Aug 2000) |
| aromatase inhibitor | Drugs, such as aminoglutethimide, that inhibit aromatase, an enzyme used in the synthesis of oestrogens. (05 Mar 2000) |
| beta-lactamase inhibitor | <pharmacology> Drugs such as clavulanic acid, which are used to inhibit bacterial beta-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance. (05 Mar 2000) |
| Bowman-Birk inhibitor | A polypeptide that will inhibit both trypsin and chymotrypsin. (05 Mar 2000) |
| C1 esterase inhibitor | An a2-neuraminoglycoprotein that inhibits the enzymatic activity of C1 esterase, the activated first component of complement. A deficiency of this inhibitor results in a lack of inhibition of C1r and C1s leading to uncontrolled activation of the complement cascade and oedema. (05 Mar 2000) |
| carbonate dehydratase inhibitor | An agent, usually chemically related to the sulfonamides, that inhibits the activity of carbonate dehydratase, producing a general decrease in the formation of H2CO3 in the tissues. See: acetazolamide, dichlorphenamide. Synonym: carbonic anhydrase inhibitor. (05 Mar 2000) |
| carbonic acid inhibitor | <pharmacology> A group of diuretic medications which act to inhibit the enzyme carbonic anhydrase to create a metabolic acidosis. Many of these medications are used in the treatment of glaucoma. (27 Sep 1997) |
| carbonic anhydrase inhibitor | <pharmacology> A group of medications (sulphonamide drugs) which inhibit the enzyme carbonic anhydrase. These medications are used in the treatment of glaucoma. Examples include acetazolamide, dichlorphenamide and methazolamide. (27 Sep 1997) |
Synonyms : Collagenase Inhibitor, TIMP, Inhibitor, Collagenase, Metalloproteinases Tissue Inhibitor
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|