| tie-over dressing | A dressing placed over a skin graft or other sutured wound and tied on by the sutures which have been left of sufficient length for that purpose. Synonym: bolus dressing. (05 Mar 2000) |
|---|---|
| tie | 1. To fasten with a band or cord and knot; to bind. "Tie the kine to the cart." "My son, keep thy father's commandment, and forsake not the law of thy mother: bind them continually upon thine heart, and tie them about thy neck." (Prov. Vi. 20,21) 2. To form, as a knot, by interlacing or complicating a cord; also, to interlace, or form a knot in; as, to tie a cord to a tree; to knit; to knot. "We do not tie this knot with an intention to puzzle the argument." 3. To unite firmly; to fasten; to hold. "In bond of virtuous love together tied." (Fairfax) 4. To hold or constrain by authority or moral influence, as by knotted cords; to oblige; to constrain; to restrain; to confine. "Not tied to rules of policy, you find Revenge less sweet than a forgiving mind." (Dryden) 5. To unite, as notes, by a cross line, or by a curved line, or slur, drawn over or under them. 6. To make an equal score with, in a contest; to be even with. To ride and tie. See Ride. To tie down. To fasten so as to prevent from rising. To restrain; to confine; to hinder from action. To tie up, to confine; to restrain; to hinder from motion or action. Origin: OE. Tien, teyen, AS. Tigan, tiegan, fr. Teag, teah, a rope; akin to Icel. Taug, and AS. Teon to draw, to pull. See Tug, and cf. Tow to drag. Origin: AS. Tege, tge, tige. 64. See Tie. 1. A knot; a fastening. 2. A bond; an obligation, moral or legal; as, the sacred ties of friendship or of duty; the ties of allegiance. "No distance breaks the tie of blood." (Young) 3. A knot of hair, as at the back of a wig. 4. An equality in numbers, as of votes, scores, etc, which prevents either party from being victorious; equality in any contest, as a race. 5. A beam or rod for holding two parts together; in railways, one of the transverse timbers which support the track and keep it in place. 6. A line, usually straight, drawn across the stems of notes, or a curved line written over or under the notes, signifying that they are to be slurred, or closely united in the performance, or that two notes of the same pitch are to be sounded as one; a bind; a ligature. 7. Low shoes fastened with lacings. Bale tie, a fastening for the ends of a hoop for a bale. Source: Websters Dictionary (01 Mar 1998) |
| TIE-2 receptor tyrosine kinase | <enzyme> Expressed in developing vascular endothelial cells; unlike tie-1, also expressed in lens epithelium and heart epicardium; has the same organization of amino acid sequence motifs characteristic of tie-1; aa sequence of the intracellular and extracellular regions of tie-1 and tie-2 are 79% and 32% identical, respectively; aa sequence of both kinases given in first source Registry number: EC 2.7.10.- Synonym: tie-2-rtk (26 Jun 1999) |
| tie receptor tyrosine kinase | <enzyme> From human leukaemia cells; expressed in developing vascular endothelial cell; has homology with egf, bfgf, csf-1, pdgf and stem cell factor receptors; ligand and biologic function not known as of 12/92; tie-1 receptor tyrosine kinase is rat homolog of tie receptor tyrosine kinase; aa sequence known Registry number: EC 2.7.10.- Synonym: tie-1 receptor tyrosine kinase, tie-1 rtk (26 Jun 1999) |
| tongue-tie | <medicine> Impeded motion of the tongue because of the shortness of the fraenum, or of the adhesion of its margins to the gums. Source: Websters Dictionary (01 Mar 1998) |
| aged, 80 and over | A person 80 years of age and older. (12 Dec 1998) |
| maternal age 35 and over | Pregnancy in women 35 or more years of age. It is used for normal pregnancies and for problems of pregnancy occurring in a woman's late reproductive years. These include effects on the mother's physical and mental health as well as risks of perinatal mortality and foetal abnormality. (12 Dec 1998) |
| crossing over | <genetics, molecular biology> The breaking during meiosis of one maternal and one paternal chromosome, the reciprocal exchange of corresponding sections of DNA along pairs of homologous chromosomes by symmetrical breakage and crosswise rejoining of the chromosomes. This results in the transfer of a block of genes from each chromosome to its homologue. In contrast to genetic recombination, which is a phenotypic phenomenon, crossing-over is genotypic. Any even number of crossing-overs between two loci will cancel out phenotypically and no recombination will occur. Recombination can result from DNA exchange of alleles between between homologous chromatids in meiosis, giving rise to chiasmata. Compare: recombination. (10 Nov 1998) |
| somatic crossing-over | Crossing-over that occurs during the mitosis of somatic cells, in contrast to that which occurs in meiosis. (05 Mar 2000) |
| drug, over-the-counter | Drug for which a prescription is not needed. (12 Dec 1998) |
| unequal crossing over | <cell biology> Crossing over between homologous chromosomes that are not precisely paired, resulting in nonreciprocal exchange of material and chromosomes of unequal length. Favoured in regions containing tandemly repeated sequences. (18 Nov 1997) |
| uneven crossing-over | Unequal crossing-over, crossing-over that happens when the breaks do not occur at precisely homologous points in two chromatid strands, and hence results in localised duplication of genetic material in one chromatid and complementary deletion in the other. (05 Mar 2000) |
| flip-over disease | <disease> A disease of young, fast-growing broiler chickens which causes them to die suddenly with a short, terminal, wing-beating convulsion, whereby they often flip over and die on their backs. (05 Mar 2000) |
| flow-over vaporiser | A device for vaporization of a liquid anaesthetic by causing gases to pass over the anaesthetic or over material saturated with the anaesthetic. (05 Mar 2000) |
| four-strand crossing over | Crossing over with both strands of DNA from each sister chromatid, so that both strands from one chromatid are exchanged for both strands on the other. This is different from the usual case where only one of the two DNA strands on one sister chromatid is exchanged for the one matching strand (of the two strands) on the other sister chromatid. (09 Oct 1997) |