| thyrotoxic serum | An antiserum obtained by injecting into animals the nucleoproteins of the thyroid gland. (05 Mar 2000) |
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| thyrotoxic | Denoting thyrotoxicosis. (05 Mar 2000) |
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| thyrotoxic coma | Coma preceding death in severe hyperthyroidism, as in thyroid storm or thyrotoxic crisis. (05 Mar 2000) |
| thyrotoxic complement-fixation factor | A form of thyrotoxin; an antigen found most readily in thyroid tissue from thyrotoxic individuals; known to be chemically and immunologically distinct from thyroglobulin, and fixes complement when combined with antibody related to the gamma-globulin fraction of serum. With the exception of extremely small concentrations, the antigen is rarely found in normal glands or in diseased glands that are not associated with thyrotoxicosis; it is probably an intracellular substance (possibly a constituent of the "microsomal fraction"), and does not contain iodine in significant quantity. Not related to the complement-fixation reaction occurring with serum in Hashimoto's disease, in which the antigen is thyroglobulin. (05 Mar 2000) |
| thyrotoxic crisis | Thyroid crisis, the exacerbation of symptoms that occurs in severe thyrotoxicosis; can follow shock or injury or thyroidectomy; marked by rapid pulse (140 to 170 per minute), nausea, diarrhoea, fever, loss of weight, extreme nervousness, and a sudden rise in the metabolic rate; coma and death may occur; occasionally the entire clinical picture is that of profound prostration, weakness, and collapse, without the phase of muscular overactivity and tachycardia. Synonym: thyroid storm. (05 Mar 2000) |
| thyrotoxic encephalopathy | A metabolic encephalopathy arising in severe cases of thyrotoxicosis. (05 Mar 2000) |
| thyrotoxic heart disease | Cardiac symptoms, signs, and physiologic impairment due to overactivity of the thyroid gland usually due to excessive sympathetic stimulation. (05 Mar 2000) |
| thyrotoxic myopathy | Extreme muscular weakness in severe thyrotoxicosis affecting muscles of limbs and trunk as well as those used in speech and swallowing. (05 Mar 2000) |
| acidified serum test | Lysis of the patient's red cells in acidified fresh serum, specific for paroxysmal nocturnal haemoglobinuria. Synonym: Ham's test. (05 Mar 2000) |
| anticomplementary serum | Serum that destroys or inactivates complement. (05 Mar 2000) |
| antiepithelial serum | An antiserum (cytotoxin) for epithelial cells. (05 Mar 2000) |
| anti-kidney serum nephritis | Experimental glomerulonephritis produced by injection of antiserum to kidney. (05 Mar 2000) |
| antilymphocyte serum | Immunoglobulins raised xenogeneically against lymphocyte populations. Referring particularly to antisera recognising one or more antigenic determinants on T-cell populations. Of use in experimental immunosuppression. (18 Nov 1997) |
| antirabies serum | A sterile solution containing antibodies obtained from the blood serum or plasma of a healthy animal, or human, that has been immunised against rabies by means of vaccine; administered immediately after severe or multiple bites by domestic animals suspected to be rabid and in all wild animal bites, to be followed by a regimen of rabies vaccine. (05 Mar 2000) |
| antireticular cytotoxic serum | An antiserum specific for cells of the reticuloendothelial system. (05 Mar 2000) |
| antitoxic serum | An antitoxin. (05 Mar 2000) |